I A in Kenyon cells resemble Shaker currents (Pelz et al 1999)

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Accession:34560
Cultured Kenyon cells from the mushroom body of the honeybee, Apis mellifera, show a voltage-gated, fast transient K1 current that is sensitive to 4-aminopyridine, an A current. The kinetic properties of this A current and its modulation by extracellular K1 ions were investigated in vitro with the whole cell patch-clamp technique. The A current was isolated from other voltage-gated currents either pharmacologically or with suitable voltage-clamp protocols. Hodgkin- and Huxley-style mathematical equations were used for the description of this current and for the simulation of action potentials in a Kenyon cell model. The data of the A current were incorporated into a reduced computational model of the voltage-gated currents of Kenyon cells. In addition, the model contained a delayed rectifier K current, a Na current, and a leakage current. The model reproduces several experimental features and makes predictions. See paper for details and results.
Reference:
1 . Pelz C, Jander J, Rosenboom H, Hammer M, Menzel R (1999) IA in Kenyon cells of the mushroom body of honeybees resembles shaker currents: kinetics, modulation by K+, and simulation. J Neurophysiol 81:1749-59 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Honeybee kenyon cell;
Channel(s): I Na,t; I A; I K;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: SNNAP;
Model Concept(s): Ion Channel Kinetics; Parameter Fitting; Action Potentials; Invertebrate;
Implementer(s): Baxter, Douglas;
Search NeuronDB for information about:  I Na,t; I A; I K;
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>----------------------->------------------------------->
	PARAMETER:	> Parameter Key word		>
>----------------------->------------------------------->
        Kv_VC.trt   > File containing the param	>
>----------------------->------------------------------->
	TRT		> Treatment param		>
>----------------------->------------------------------->
	2		>  cinj=0			>
			>  minj=1			>
			>  vclmp=2			>
			>  iclmp=3			>
>----------------------->------------------------------->
	1		> which treatment		>
			> start from 0			>
>----------------------->------------------------------->
	2		> start_t=0			>
			> stop_t=1			>
			> magn=2			>
>----------------------->------------------------------->
	0		> Manual Incr =0		>
			> Auto Incr =1			>
>----------------------->------------------------------->
	5		> number of values		>
>----------------------->------------------------------->
	-50		> one value 			>
>----------------------->------------------------------->
	-35		> one value 			>
>----------------------->------------------------------->
	-20		> one value 			>
>----------------------->------------------------------->
	 -5		> one value 			>
>----------------------->------------------------------->
	 10		> one value 			>
>----------------------->------------------------------->

>----------------------->------------------------------->
>	PARAMETER:	> Parameter Key word		>
>----------------------->------------------------------->
>       filename.trt   > File containing the param	>
>----------------------->------------------------------->
>	TRT		> Treatment param		>
>----------------------->------------------------------->
>	0		>  cinj=0			>
>			>  minj=1			>
>			>  vclmp=2			>
>			>  iclmp=3			>
>----------------------->------------------------------->
>	1		> which treat			>
>			> start from 0			>
>----------------------->------------------------------->
>	1		> start_t=0			>
>			> stop_t=1			>
>			> magn=2			>
>----------------------->------------------------------->
>	0		> Manual Incr =0		>
>			> Auto Incr =1			>
>----------------------->------------------------------->
>	7		> number of values		>
>----------------------->------------------------------->
>	0.014		> one value 			>
>----------------------->------------------------------->
>	0.016		> one value 			>
>----------------------->------------------------------->
>	0.018		> one value 			>
>----------------------->------------------------------->
>	0.020		> one value 			>
>----------------------->------------------------------->
>	0.022		> one value 			>
>----------------------->------------------------------->
>	0.024		> one value 			>
>----------------------->------------------------------->
>	0.026		> one value 			>
>----------------------->-------------------------------> 

>----------------------->------------------------------->
>	PARAMETER:	> Parameter Key word		>
>----------------------->------------------------------->
>    filename.neu        > File containing the param	>
>----------------------->------------------------------->
>	NEU		> Neuron param			>
>----------------------->------------------------------->
>	3		>  0 = threshold		>
>			>  1 = spikdur                  >
>			>  2 = vmint                    >
>			>  3 = cm                       >
>----------------------->------------------------------->
>	1		> 0 = Manual Incr               >
>			> 1 = Auto Incr			>
>----------------------->------------------------------->
>	0.001           > start value			>
>----------------------->------------------------------->
>	0.001           > increment			>
>----------------------->------------------------------->
>	0.08            > stop value			>
>----------------------->------------------------------->

>--------------------------------------->------------------------------->
>	PARAMETER:			> One parameter			>
>--------------------------------------->------------------------------->
>	K.vdg				> the file containg the param   >
>--------------------------------------->------------------------------->
>	FMU				> File type is formula		>
>--------------------------------------->------------------------------->
>	Ivd:				> keyword in formula file	>
>--------------------------------------->------------------------------->
>	0				> which parameter under keyword >
>					> start counting with 0		>
>--------------------------------------->------------------------------->
>	0				> 0 =manual 			>
>					> 1=auto increment   		>
>--------------------------------------->------------------------------->
>	5				> number of parameter values    >
>--------------------------------------->------------------------------->
>	25.5				> one value			>
>--------------------------------------->------------------------------->
>	12.9				> one value			>
>--------------------------------------->------------------------------->
>	8.4				> one parameter value		>
>--------------------------------------->------------------------------->
>	5.9				> one parameter value		>
>--------------------------------------->------------------------------->
>	3.2				> one parameter value		>
>--------------------------------------->------------------------------->