Arteriolar networks: Spread of potential (Crane et al 2001)

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Accession:3785
Crane, G.J., Hines, M.L., and Neild, T.O. (2001) Simulating the spread of membrane potential changes in arteriolar networks. Microcirculation 8:33-43. This model uses a gap junction density mechanism to couple arteriolar smooth muscle and endothelium in microvascular trees.
Reference:
1 . Crane GJ, Hines ML, Neild TO (2001) Simulating the spread of membrane potential changes in arteriolar networks. Microcirculation 8:33-43 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type:
Brain Region(s)/Organism:
Cell Type(s): Arteriolar network;
Channel(s):
Gap Junctions: Gap junctions;
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s):
Implementer(s): Hines, Michael [Michael.Hines at Yale.edu]; Crane, Glenis J [prsgjc at bath.ac.uk];
load_file("nrngui.hoc")
objectvar save_window_, rvp_
objectvar scene_vector_[4]
objectvar ocbox_, ocbox_list_, scene_, scene_list_
{ocbox_list_ = new List()  scene_list_ = new List()}
{pwman_place(0,0,0)}
{
xpanel("RunControl", 0)
v_init = 0
xvalue("Init","v_init", 1,"stdinit()", 1, 1 )
xbutton("Init & Run","run()")
xbutton("Stop","stoprun=1")
runStopAt = 5
xvalue("Continue til","runStopAt", 1,"{continuerun(runStopAt) stoprun=1}", 1, 1 )
runStopIn = 1
xvalue("Continue for","runStopIn", 1,"{continuerun(t + runStopIn) stoprun=1}", 1, 1 )
xbutton("Single Step","steprun()")
t = 500
xvalue("t","t", 2 )
tstop = 500
xvalue("Tstop","tstop", 1,"tstop_changed()", 0, 1 )
dt = 21.1238
xvalue("dt","dt", 1,"setdt()", 0, 1 )
steps_per_ms = 1
xvalue("Points plotted/ms","steps_per_ms", 1,"setdt()", 0, 1 )
xcheckbox("Quiet",&stdrun_quiet,"")
realtime = 0
xvalue("Real Time","realtime", 0,"", 0, 1 )
xpanel(59,112)
}
{
save_window_ = new PlotShape(0)
save_window_.size(144.774,3901.8,-2091.03,1660.01)
save_window_.variable("v")
scene_vector_[2] = save_window_
{save_window_.view(144.774, -2091.03, 3757.03, 3751.04, 383, 25, 200.64, 200.32)}
fast_flush_list.append(save_window_)
save_window_.save_name("fast_flush_list.")
}
{
save_window_ = new Graph(0)
save_window_.size(0,5000,0,1)
scene_vector_[3] = save_window_
{save_window_.view(0, 0, 5000, 1, 609, 28, 300.48, 200.32)}
flush_list.append(save_window_)
save_window_.save_name("flush_list.")
objectvar rvp_
rvp_ = new RangeVarPlot("v")
mcab[0] rvp_.begin(0)
mcab[0] rvp_.end(1)
rvp_.origin(0)
save_window_.addobject(rvp_, 2, 1, -1, 0)
objectvar rvp_
rvp_ = new RangeVarPlot("v")
mcab[1] rvp_.begin(0)
mcab[1] rvp_.end(1)
rvp_.origin(2000)
save_window_.addobject(rvp_, 2, 1, -1, 0)
objectvar rvp_
rvp_ = new RangeVarPlot("v")
mcab[2] rvp_.begin(0)
mcab[2] rvp_.end(1)
rvp_.origin(2000)
save_window_.addobject(rvp_, 2, 1, -1, 0)
objectvar rvp_
rvp_ = new RangeVarPlot("v")
mcab[3] rvp_.begin(0)
mcab[3] rvp_.end(1)
rvp_.origin(2350)
save_window_.addobject(rvp_, 2, 1, -1, 0)
objectvar rvp_
rvp_ = new RangeVarPlot("v")
mcab[4] rvp_.begin(0)
mcab[4] rvp_.end(1)
rvp_.origin(2350)
save_window_.addobject(rvp_, 2, 1, -1, 0)
objectvar rvp_
rvp_ = new RangeVarPlot("v")
mcab[5] rvp_.begin(0)
mcab[5] rvp_.end(1)
rvp_.origin(2720)
save_window_.addobject(rvp_, 2, 1, -1, 0)
objectvar rvp_
rvp_ = new RangeVarPlot("v")
mcab[6] rvp_.begin(0)
mcab[6] rvp_.end(1)
rvp_.origin(2720)
save_window_.addobject(rvp_, 2, 1, -1, 0)
objectvar rvp_
rvp_ = new RangeVarPlot("v")
ecab[0] rvp_.begin(0)
ecab[0] rvp_.end(1)
rvp_.origin(0)
save_window_.addobject(rvp_, 1, 1, -1, 0)
objectvar rvp_
rvp_ = new RangeVarPlot("v")
ecab[1] rvp_.begin(0)
ecab[1] rvp_.end(1)
rvp_.origin(2000)
save_window_.addobject(rvp_, 1, 1, -1, 0)
objectvar rvp_
rvp_ = new RangeVarPlot("v")
ecab[2] rvp_.begin(0)
ecab[2] rvp_.end(1)
rvp_.origin(2000)
save_window_.addobject(rvp_, 1, 1, -1, 0)
objectvar rvp_
rvp_ = new RangeVarPlot("v")
ecab[3] rvp_.begin(0)
ecab[3] rvp_.end(1)
rvp_.origin(2350)
save_window_.addobject(rvp_, 1, 1, -1, 0)
objectvar rvp_
rvp_ = new RangeVarPlot("v")
ecab[4] rvp_.begin(0)
ecab[4] rvp_.end(1)
rvp_.origin(2350)
save_window_.addobject(rvp_, 1, 1, -1, 0)
objectvar rvp_
rvp_ = new RangeVarPlot("v")
ecab[5] rvp_.begin(0)
ecab[5] rvp_.end(1)
rvp_.origin(2720)
save_window_.addobject(rvp_, 1, 1, -1, 0)
objectvar rvp_
rvp_ = new RangeVarPlot("v")
ecab[6] rvp_.begin(0)
ecab[6] rvp_.end(1)
rvp_.origin(2720)
save_window_.addobject(rvp_, 1, 1, -1, 0)
save_window_.label(0.380192, 0.829074, "endothelium", 2, 1, 0, 0, 1)
save_window_.label(0.421725, 0.71885, "muscle", 2, 1, 0, 0, 2)
}
{
xpanel("Figures", 0)
xbutton("Figure 3 1A in vitro","cvode_active(1) fig1A_vitro()")
xbutton("Figure 4 2A in vitro","cvode_active(1) mcab[0] othervitro(10000)")
xbutton("Figure 4 2A' in vitro","cvode_active(1) ecab[0] othervitro(10000)")
xbutton("Figure 5 3A in vitro","cvode_active(0) mcab[0] othervitro(100)")
xbutton("Figure 5 3A' in vitro","cvode_active(0) ecab[0] othervitro(100)")
xpanel(380,296)
}
objectvar scene_vector_[1]
{doNotify()}