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Olfactory Mitral cell: AP initiation modes (Chen et al 2002)
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Model Information
Model File
Simulation Platform
Accession:
3793
The mitral cell primary dendrite plays an important role in transmitting distal olfactory nerve input from olfactory glomerulus to the soma-axon initial segment. To understand how dendritic active properties are involved in this transmission, we have combined dual soma and dendritic patch recordings with computational modeling to analyze action-potential initiation and propagation in the primary dendrite.
Reference:
1 .
Chen WR, Shen GY, Shepherd GM, Hines ML, Midtgaard J (2002) Multiple modes of action potential initiation and propagation in mitral cell primary dendrite.
J Neurophysiol
88
:2755-64
[
PubMed
]
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Model Information
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Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Olfactory bulb main mitral GLU cell;
Myelinated neuron;
Channel(s):
I Na,t;
I K;
Gap Junctions:
Receptor(s):
AMPA;
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Action Potential Initiation;
Synaptic Integration;
Olfaction;
Implementer(s):
Hines, Michael [Michael.Hines at Yale.edu];
Search NeuronDB
for information about:
Olfactory bulb main mitral GLU cell
;
AMPA
;
I Na,t
;
I K
;
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chen2002
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