Olfactory Mitral cell: AP initiation modes (Chen et al 2002)

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The mitral cell primary dendrite plays an important role in transmitting distal olfactory nerve input from olfactory glomerulus to the soma-axon initial segment. To understand how dendritic active properties are involved in this transmission, we have combined dual soma and dendritic patch recordings with computational modeling to analyze action-potential initiation and propagation in the primary dendrite.
1 . Chen WR, Shen GY, Shepherd GM, Hines ML, Midtgaard J (2002) Multiple modes of action potential initiation and propagation in mitral cell primary dendrite. J Neurophysiol 88:2755-64 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Olfactory bulb main mitral GLU cell; Myelinated neuron;
Channel(s): I Na,t; I K;
Gap Junctions:
Receptor(s): AMPA;
Simulation Environment: NEURON;
Model Concept(s): Action Potential Initiation; Synaptic Integration; Olfaction;
Implementer(s): Hines, Michael [Michael.Hines at Yale.edu];
Search NeuronDB for information about:  Olfactory bulb main mitral GLU cell; AMPA; I Na,t; I K;
To simulate the electrode we add a small section to
serve as the electrode resistance and capacitance

watch out when changing Ra in the model since this
electrode.Ra is used for the series resistance!

begintemplate Electrode

public electrode
create electrode

// c (pf) = cm*area = PI*L*diam*(.01) * cm
// rs (MOhm) = Ra*L/2 / (PI*diam^2/4) = 2*L/PI/diam^2 * (.01) * Ra

// so it is nice to have
// PI*L*diam*.01 = 1
// 2*L/PI/diam^2*.01 = 1

// diam = (2/PI^2)^(1/3)
// L = 1/.01/PI/diam

proc init_electrode() {
	electrode {
		diam = (2/PI^2)^(1/3)
		L = 1/.01/PI/diam
		insert pas
		g_pas = 0
		e_pas = 0

proc init() {
        electrode Ra = 0.001		//(Ohm*cm)
        electrode cm = 0		//(uF/cm2)
        connect electrode(0), $1

//electrode makeppm()

endtemplate Electrode