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Olfactory bulb granule cell: effects of odor deprivation (Saghatelyan et al 2005)
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The model supports the experimental findings on the effects of postnatal odor deprivation, and shows that a -10mV shift in the Na activation or a reduction in the dendritic length of newborn GC could independently explain the observed increase in excitability.
Saghatelyan A, Roux P, Migliore M, Rochefort C, Desmaisons D, Charneau P, Shepherd GM, Lledo PM (2005) Activity-dependent adjustments of the inhibitory network in the olfactory bulb following early postnatal deprivation.
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Olfactory bulb main mitral GLU cell;
Olfactory bulb main interneuron granule MC GABA cell;
Action Potential Initiation;
Ion Channel Kinetics;
Influence of Dendritic Geometry;
Migliore, Michele [Michele.Migliore at Yale.edu];
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Olfactory bulb main mitral GLU cell
Olfactory bulb main interneuron granule MC GABA cell
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