Channel parameter estimation from current clamp and neuronal properties (Toth, Crunelli 2001)

 Download zip file 
Help downloading and running models
Accession:54154
In this paper, we present a method by which the activation and kinetic properties of INa, IK can be estimated from current-clamp data, more precisely from the time course of the action potential, provided some additional electrophysiological properties of the neurone are a priori known. See reference for details and more.
Reference:
1 . Tóth TI, Crunelli V (2001) Estimation of the activation and kinetic properties of I(Na) and I(K) from the time course of the action potential. J Neurosci Methods 111:111-26 [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Channel/Receptor;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: Octave;
Model Concept(s): Ion Channel Kinetics; Methods;
Implementer(s): Toth, T.I [toth at cardiff.ac.uk];