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Simulated light response in rod photoreceptors (Liu and Kourennyi 2004)
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We developed a complete computer model of the rod, which accurately reproduced the main features of the light response and allowed us to demonstrate that it was suppression of Kx channels that was essential for slowing SLR and increasing excitability of rods. The results reported in this work further establish the importance of Kx channels in rod photoreceptor function.
Liu XD, Kourennyi DE (2004) Effects of tetraethylammonium on Kx channels and simulated light response in rod photoreceptors.
Ann Biomed Eng
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Neuron or other electrically excitable cell;
Retina photoreceptor cone GLU cell;
I L high threshold;
Action Potential Initiation;
Kourennyi, Dmitri E [dek at case.edu];
Liu, Xiaodong [xliu22 at jhmi.edu];
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Retina photoreceptor cone GLU cell
I L high threshold
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fig 8B. AP_BR
fig 8D. AP_DIM