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CA3 pyramidal neuron: firing properties (Hemond et al. 2008)
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Accession:
101629
In the paper, this model was used to identify how relative differences in K+ conductances, specifically KC, KM, & KD, between cells contribute to the different characteristics of the three types of firing patterns observed experimentally.
Reference:
1 .
Hemond P, Epstein D, Boley A, Migliore M, Ascoli GA, Jaffe DB (2008) Distinct classes of pyramidal cells exhibit mutually exclusive firing patterns in hippocampal area CA3b.
Hippocampus
18
:411-24
[
PubMed
]
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Model Information
(Click on a link to find other models with that property)
Model Type:
Dendrite;
Brain Region(s)/Organism:
Cell Type(s):
Hippocampus CA3 pyramidal GLU cell;
Channel(s):
I Na,t;
I L high threshold;
I T low threshold;
I A;
I K;
I M;
I h;
I K,Ca;
I CAN;
I Calcium;
I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Bursting;
Active Dendrites;
Detailed Neuronal Models;
Action Potentials;
Implementer(s):
Migliore, Michele [Michele.Migliore at Yale.edu];
Search NeuronDB
for information about:
Hippocampus CA3 pyramidal GLU cell
;
I Na,t
;
I L high threshold
;
I T low threshold
;
I A
;
I K
;
I M
;
I h
;
I K,Ca
;
I CAN
;
I Calcium
;
I Potassium
;
/
ca3b
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Fig.9B
Fig.9C
Fig.9D
Fig.9E