Gap junction coupled network of striatal fast spiking interneurons (Hjorth et al. 2009)

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Accession:118389
Gap junctions between striatal FS neurons has very weak ability to synchronise spiking. Input uncorrelated between neighbouring neurons is shunted, while correlated input is not.
Reference:
1 . Hjorth J, Blackwell KT, Kotaleski JH (2009) Gap junctions between striatal fast-spiking interneurons regulate spiking activity and synchronization as a function of cortical activity. J Neurosci 29:5276-86 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network; Neuron or other electrically excitable cell; Synapse; Channel/Receptor; Dendrite;
Brain Region(s)/Organism: Basal ganglia;
Cell Type(s): Neostriatum fast spiking interneuron;
Channel(s): I A; I_K,Na;
Gap Junctions: Gap junctions;
Receptor(s):
Gene(s):
Transmitter(s): Gaba; Glutamate;
Simulation Environment: GENESIS; MATLAB;
Model Concept(s): Activity Patterns; Ion Channel Kinetics; Synchronization; Detailed Neuronal Models;
Implementer(s): Hjorth, Johannes [hjorth at csc.kth.se];
Search NeuronDB for information about:  I A; I_K,Na; Gaba; Glutamate;
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FSGJ_Hjorth2009
FIGS5
BlueGene
FIGS
INDATA
UTDATA
a_channel.g *
a_channel_MOD.g
ampa_channel.g *
channelsMOD.g
channelsSobol.g
channelsSobolSynch.g
checkAllEqual.m *
findSpikes.m *
fsConnect.g *
fsInhomogeneNeurons.g *
fsInputFromFile.g
fsInputInject.g *
fsNeuron.g *
fsSomaOutput.g *
gaba_channel.g *
inspectTrace.m
k13_channel.g *
k13_channel_MOD.g
k3132_channel.g *
k3132_channel_MOD.g
makeAllSynapticInput.m
makeCorrPairFigure.m
makeDaughterNoise.m *
makeFSMorph.m
makeFSMorphMOD.m
makeFSrandomNetwork.m
makeShuffleCorrCrossCorr.m
makeShuntingSensitivityFigure.m
makeTrainNoise.m *
na_channel.g *
na_channel_MOD.g
poissonMaxTime.m *
protodefs.g
protodefsInhomogene.g
protodefsMOD.g
protodefsSobol.g
protodefsSobolSynch.g
readTenFSsensitivity.m
readTenFSsensitivityOLD.m
runFSsensitivity.m
runTenFSsensitivity.m
simFourFSsaveGJcur.g
writeFSMODinfo.m
writeInput.m *
writeSobolSynchInfo.m
                            
%
% Generates 2Hz square waves with 0.5 dutycycle.
%

function noise = makeTrainNoise(corrRudolph, nTrains, freq, maxTime)

  nRudolph = nTrains - sqrt(corrRudolph)*(nTrains-1);
  
  allSpikes = poissonMaxTime(freq*nRudolph, maxTime);
  
  for i=1:nTrains
    finalSpikes{i} = [];
  end
  
  for i=1:length(allSpikes)
     repeats = nTrains / nRudolph;
     repeats = floor(repeats) + (rand(1) < mod(repeats,1));

     freeTrains = 1:nTrains;
     
     for j=1:repeats
         idx = ceil(length(freeTrains)*rand(1));
         trainIdx = freeTrains(idx);
         freeTrains(idx) = [];
         
         finalSpikes{trainIdx} = [finalSpikes{trainIdx}; allSpikes(i)];
     end     
  end

  
  for i=1:nTrains
     trainLen(i) = length(finalSpikes{i}); 
  end

  maxLen = max(trainLen); 
  noise = inf*ones(maxLen,nTrains);

  for i=1:nTrains
     noise(1:length(finalSpikes{i}),i) = finalSpikes{i}; 
      
  end