Advanced search
User account
Login
Register
Find models by
Model name
First author
Each author
Find models for
Brain region
Concept
Find models of
Realistic Microcircuits
Connectionist Networks
Mechanisms of magnetic stimulation of central nervous system neurons (Pashut et al. 2011)
Download zip file
Auto-launch
Help downloading and running models
Model Information
Model File
Model Views
Accession:
138321
Transcranial magnetic stimulation (TMS) is a widely applied tool for probing cognitive function in humans and is one of the best tools for clinical treatments and interfering with cognitive tasks. Surprisingly, while TMS has been commercially available for decades, the cellular mechanisms underlying magnetic stimulation remain unclear. Here we investigate these mechanisms using compartmental modeling. We generated a numerical scheme allowing simulation of the physiological response to magnetic stimulation of neurons with arbitrary morphologies and active properties. Computational experiments using this scheme suggested that TMS affects neurons in the central nervous system (CNS) primarily by somatic stimulation.
Reference:
1 .
Pashut T, Wolfus S, Friedman A, Lavidor M, Bar-Gad I, Yeshurun Y, Korngreen A (2011) Mechanisms of magnetic stimulation of central nervous system neurons.
PLoS Comput Biol
7
:e1002022
[
PubMed
]
Citations
Citation Browser
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Neocortex L5/6 pyramidal GLU cell;
Squid axon;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
MATLAB;
Model Concept(s):
Action Potential Initiation;
Magnetic stimulation;
Implementer(s):
Korngreen, Alon [alon.korngreen at gmail.com];
Pashut, Tamar [tamar.pashut at gmail.com];
Search NeuronDB
for information about:
Neocortex L5/6 pyramidal GLU cell
;
/
pashut2011
OneDimension
TwoDimensions
readme.txt
mosinit.hoc
File not selected
<- Select file from this column.
Load Model View