:Comment : The persistent component of the K current
:Reference : : Voltagegated K+ channels in layer 5 neocortical pyramidal neurones from young rats:subtypes and gradients,Korngreen and Sakmann, J. Physiology, 2000
:Comment : shifted 10 mv to correct for junction potential
:Comment: corrected rates using q10 = 2.3, target temperature 34, orginal 21
NEURON {
SUFFIX K_Pst
USEION k READ ek WRITE ik
RANGE gK_Pstbar, gK_Pst, ik
}
UNITS {
(S) = (siemens)
(mV) = (millivolt)
(mA) = (milliamp)
}
PARAMETER {
gK_Pstbar = 0.00001 (S/cm2)
}
ASSIGNED {
v (mV)
ek (mV)
ik (mA/cm2)
gK_Pst (S/cm2)
mInf
mTau (ms)
hInf
hTau (ms)
}
STATE {
m
h
}
BREAKPOINT {
SOLVE states METHOD cnexp
gK_Pst = gK_Pstbar*m*m*h
ik = gK_Pst*(vek)
}
DERIVATIVE states {
rates()
m' = (mInfm)/mTau
h' = (hInfh)/hTau
}
INITIAL{
rates()
m = mInf
h = hInf
}
PROCEDURE rates(){
LOCAL qt
qt = 2.3^((3421)/10)
UNITSOFF
v = v + 10
mInf = (1/(1 + exp((v+1)/12)))
if(v<50){
mTau = (1.25+175.03*exp(v * 0.026))/qt
}else{
mTau = ((1.25+13*exp(v*0.026)))/qt
}
hInf = 1/(1 + exp((v+54)/11))
hTau = (360+(1010+24*(v+55))*exp(((v+75)/48)^2))/qt
v = v  10
UNITSON
}
