Shaping of action potentials by different types of BK channels (Jaffe et al., 2011)

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Accession:140471
Dentate gyrus granule cells highly express the beta4 accessory subunit which confer BK channels with type II properties. The properties of heterologously-expressed BK channels (with and without the beta4 subunit) were used to construct channel models. These were then used to study how they affect single action potentials and trains of spikes in a model dentate gyrus granule cells (based on Aradi and Holmes, 1999).
Reference:
1 . Jaffe DB, Wang B, Brenner R (2011) Shaping of action potentials by type I and type II large-conductance Ca²+-activated K+ channels. Neuroscience 192:205-18 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Dentate gyrus granule GLU cell;
Channel(s): I K,Ca;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potentials;
Implementer(s): Jaffe, David B [david.jaffe at utsa.edu];
Search NeuronDB for information about:  Dentate gyrus granule GLU cell; I K,Ca;
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28.9 -69.249 7e-05 4.49382e-11
28.925 -69.2497 7e-05 4.49133e-11
28.95 -69.2503 7e-05 4.48885e-11
28.975 -69.2509 7e-05 4.48639e-11
29 -69.2515 7e-05 4.48394e-11
29.025 -69.2521 7e-05 4.4815e-11
29.05 -69.2527 7e-05 4.47908e-11
29.075 -69.2534 7e-05 4.47667e-11
29.1 -69.254 7e-05 4.47427e-11
29.125 -69.2546 7e-05 4.47189e-11
29.15 -69.2552 7e-05 4.46952e-11
29.175 -69.2558 7e-05 4.46716e-11
29.2 -69.2564 7e-05 4.46482e-11
29.225 -69.257 7e-05 4.46249e-11
29.25 -69.2576 7e-05 4.46017e-11
29.275 -69.2582 7e-05 4.45786e-11
29.3 -69.2589 7e-05 4.45557e-11
29.325 -69.2595 7e-05 4.45329e-11
29.35 -69.2601 7e-05 4.45102e-11
29.375 -69.2607 7e-05 4.44877e-11
29.4 -69.2613 7e-05 4.44652e-11
29.425 -69.2619 7e-05 4.44429e-11
29.45 -69.2625 7e-05 4.44207e-11
29.475 -69.2631 7e-05 4.43987e-11
29.5 -69.2637 7e-05 4.43767e-11
29.525 -69.2643 7e-05 4.43549e-11
29.55 -69.2649 7e-05 4.43332e-11
29.575 -69.2655 7e-05 4.43116e-11
29.6 -69.2661 7e-05 4.42901e-11
29.625 -69.2667 7e-05 4.42688e-11
29.65 -69.2673 7e-05 4.42475e-11
29.675 -69.2679 7e-05 4.42264e-11
29.7 -69.2685 7e-05 4.42054e-11
29.725 -69.2691 7e-05 4.41845e-11
29.75 -69.2697 7e-05 4.41637e-11
29.775 -69.2703 7e-05 4.4143e-11
29.8 -69.2709 7e-05 4.41225e-11
29.825 -69.2715 7e-05 4.4102e-11
29.85 -69.272 7e-05 4.40817e-11
29.875 -69.2726 7e-05 4.40615e-11
29.9 -69.2732 7e-05 4.40413e-11
29.925 -69.2738 7e-05 4.40213e-11
29.95 -69.2744 7e-05 4.40014e-11
29.975 -69.275 7e-05 4.39816e-11