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Spike repolarization in axon collaterals (Foust et al. 2011)
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Accession:
143442
Voltage sensing dye experiments and simulations characterize the location and re-polarizing function of Kv1 channels in cortical neurons. "... (the papers) results indicate that action potential-induced synaptic transmission may operate through a mix of analog–digital transmission owing to the properties of Kv1 channels in axon collaterals and presynaptic boutons."
Reference:
1 .
Foust AJ, Yu Y, Popovic M, Zecevic D, McCormick DA (2011) Somatic membrane potential and Kv1 channels control spike repolarization in cortical axon collaterals and presynaptic boutons.
J Neurosci
31
:15490-8
[
PubMed
]
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Model Information
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Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Neocortex L5/6 pyramidal GLU cell;
Neocortex L2/3 pyramidal GLU cell;
Channel(s):
I Na,t;
I K;
I_KD;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Action Potentials;
Implementer(s):
Search NeuronDB
for information about:
Neocortex L5/6 pyramidal GLU cell
;
Neocortex L2/3 pyramidal GLU cell
;
I Na,t
;
I K
;
I_KD
;
/
FoustEtAl2011
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