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Synchrony by synapse location (McTavish et al. 2012)
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Model Information
Model File
Accession:
144054
This model considers synchrony between mitral cells induced via shared granule cell interneurons while taking into account the spatial constraints of the system. In particular, since inhibitory inputs decay passively along the lateral dendrites, this model demonstrates that an optimal arrangement of the inhibitory synapses will be near the cell bodies of the relevant mitral cells.
Reference:
1 .
McTavish TS, Migliore M, Shepherd GM, Hines ML (2012) Mitral cell spike synchrony modulated by dendrodendritic synapse location.
Front Comput Neurosci
6
:3
[
PubMed
]
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Model Information
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Model Type:
Realistic Network;
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Olfactory bulb;
Cell Type(s):
Olfactory bulb main mitral GLU cell;
Olfactory bulb main interneuron granule MC GABA cell;
Channel(s):
I Na,t;
I A;
I K;
Gap Junctions:
Receptor(s):
GabaB;
AMPA;
NMDA;
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Synchronization;
Olfaction;
Implementer(s):
McTavish, Thomas S [thomas.mctavish at yale.edu];
Search NeuronDB
for information about:
Olfactory bulb main mitral GLU cell
;
Olfactory bulb main interneuron granule MC GABA cell
;
GabaB
;
AMPA
;
NMDA
;
I Na,t
;
I A
;
I K
;
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mctavish_syncbylocation
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