Dendro-dendritic synaptic circuit (Shepherd Brayton 1979)

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Accession:144385
A NEURON simulation has been created to model the passive spread of an EPSP from a mitral cell synapse on a granule cell spine. The EPSP was shown to propagate subthreshold through the dendritic shaft into an adjacent spine with significant amplitude (figure 2B).
Reference:
1 . Shepherd GM, Brayton RK (1979) Computer simulation of a dendrodendritic synaptic circuit for self- and lateral-inhibition in the olfactory bulb. Brain Res 175:377-82 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Influence of Dendritic Geometry; Olfaction;
Implementer(s): Morse, Tom [Tom.Morse at Yale.edu];
// extra_dendrite.hoc
// explores effect of adding extra compartments to the ends of the
// existing dendrite in the model

create dendrite_top, dendrite_bottom
// dendrite_bottom connect dendrite(0), 1
// dendrite connect dendrite_top(0), 1

dendrite_bottom connect GR_5(0), 1
GR_10 connect dendrite_top(0), 1

dendrite_top { insert pas L=70 diam=1 e_pas=-80}
dendrite_bottom {insert pas L=70 diam=1 e_pas=-80}

objref shaft
shaft=new SectionList()
forsec "GR" shaft.append()
forsec "dendrite" shaft.append()