Dendro-dendritic synaptic circuit (Shepherd Brayton 1979)

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Accession:144385
A NEURON simulation has been created to model the passive spread of an EPSP from a mitral cell synapse on a granule cell spine. The EPSP was shown to propagate subthreshold through the dendritic shaft into an adjacent spine with significant amplitude (figure 2B).
Reference:
1 . Shepherd GM, Brayton RK (1979) Computer simulation of a dendrodendritic synaptic circuit for self- and lateral-inhibition in the olfactory bulb. Brain Res 175:377-82 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Influence of Dendritic Geometry; Olfaction;
Implementer(s): Morse, Tom [Tom.Morse at Yale.edu];
// gr_ dendrite_morphology.hoc
// create a simple granule cell dendrite to which spines can be added.
// Shepherd Brayton 1987 fig 1

create GR_5, GR_6, GR_7, GR_8, GR_9, GR_10

GR_5 connect GR_6(0), 1
GR_6 connect GR_7(0), 1
GR_7 connect GR_8(0), 1
GR_8 connect GR_9(0), 1
GR_9 connect GR_10(0), 1

forsec "GR" {
  L=70
  diam=1
  insert pas
  e_pas=-80
}