NMDA subunit effects on Calcium and STDP (Evans et al. 2012)

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Accession:145917
Effect of NMDA subunit on spike timing dependent plasticity.
Reference:
1 . Evans RC, Morera-Herreras T, Cui Y, Du K, Sheehan T, Kotaleski JH, Venance L, Blackwell KT (2012) The effects of NMDA subunit composition on calcium influx and spike timing-dependent plasticity in striatal medium spiny neurons. PLoS Comput Biol 8:e1002493 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Neostriatum medium spiny direct pathway GABA cell;
Channel(s): I Na,t; I L high threshold; I T low threshold; I A; I h; I K,Ca; I Calcium; I A, slow;
Gap Junctions:
Receptor(s): GabaA; Glutamate;
Gene(s):
Transmitter(s):
Simulation Environment: GENESIS;
Model Concept(s): STDP; Calcium dynamics;
Implementer(s): Blackwell, Avrama [avrama at gmu.edu]; Evans, Rebekah [Rebekah.Evans at nih.gov];
Search NeuronDB for information about:  Neostriatum medium spiny direct pathway GABA cell; GabaA; Glutamate; I Na,t; I L high threshold; I T low threshold; I A; I h; I K,Ca; I Calcium; I A, slow;
//genesis
//  synaptic_channel.g

/***************************		MS Model, Version 7.6	*********************
**************************** 	      synaptic_channel.g  	*********************
	Avrama Blackwell 	kblackw1@gmu.edu
	Rebekah Evans 		rcolema2@gmu.edu	
	Tom Sheehan 		tsheeha2@gmu.edu	
******************************************************************************

*****************************************************************************/

function make_synaptic_channel (chanpath, tau1, tau2, gmax, Ek)
   str chanpath
   float tau1
   float tau2
   float gmax 
   float Ek

/*	echo "XXXXXXXXXXXXXXX make_synaptic_channel XXXXXXXXXXXXXXXX"
	echo "chanpath = "{chanpath}
	echo "tau1 = "{tau1}
	echo "tau2 = "{tau2}
	echo "gmax = "{gmax}
	echo "XXXXXXXXXXXXXXX make_synaptic_channel XXXXXXXXXXXXXXXX"
*/
   create synchan {chanpath}

   setfield {chanpath} tau1 {tau1} \
                       tau2 {tau2}\ 
                       gmax {gmax}\
                        Ek {Ek}

end