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A set of reduced models of layer 5 pyramidal neurons (Bahl et al. 2012)
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Model Information
Model File
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Accession:
146026
These are the NEURON files for 10 different models of a reduced L5 pyramidal neuron. The parameters were obtained by automatically fitting the models to experimental data using a multi objective evolutionary search strategy. Details on the algorithm can be found at http://www.g-node.org/emoo and in Bahl et al. (2012).
Reference:
1 .
Bahl A, Stemmler MB, Herz AV, Roth A (2012) Automated optimization of a reduced layer 5 pyramidal cell model based on experimental data.
J Neurosci Methods
210
:22-34
[
PubMed
]
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Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Dendrite;
Brain Region(s)/Organism:
Cell Type(s):
Neocortex U1 L5B pyramidal pyramidal tract GLU cell;
Channel(s):
I Na,p;
I Na,t;
I K;
I M;
I h;
I K,Ca;
I Calcium;
I A, slow;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Action Potential Initiation;
Parameter Fitting;
Simplified Models;
Active Dendrites;
Detailed Neuronal Models;
Action Potentials;
Methods;
Calcium dynamics;
Implementer(s):
Bahl, Armin [bahl at neuro.mpg.de];
Search NeuronDB
for information about:
Neocortex U1 L5B pyramidal pyramidal tract GLU cell
;
I Na,p
;
I Na,t
;
I K
;
I M
;
I h
;
I K,Ca
;
I Calcium
;
I A, slow
;
/
BahlEtAl2012
channels
cad.mod
*
Other models using cad.mod:
A model of optimal learning with redundant synaptic connections (Hiratani & Fukai 2018)
Altered complexity in layer 2/3 pyramidal neurons (Luuk van der Velden et al. 2012)
Cortical pyramidal neuron, phase response curve (Stiefel et al 2009)
Engaging distinct oscillatory neocortical circuits (Vierling-Claassen et al. 2010)
h.mod
IKM.mod
kca.mod
*
Other models using kca.mod:
A model of optimal learning with redundant synaptic connections (Hiratani & Fukai 2018)
AP back-prop. explains threshold variability and rapid rise (McCormick et al. 2007, Yu et al. 2008)
Altered complexity in layer 2/3 pyramidal neurons (Luuk van der Velden et al. 2012)
Compartmentalization of GABAergic inhibition by dendritic spines (Chiu et al. 2013)
Cortical pyramidal neuron, phase response curve (Stiefel et al 2009)
Dendritic Discrimination of Temporal Input Sequences (Branco et al. 2010)
Engaging distinct oscillatory neocortical circuits (Vierling-Claassen et al. 2010)
Intracortical synaptic potential modulation by presynaptic somatic potential (Shu et al. 2006, 2007)
Stochastic Ih and Na-channels in pyramidal neuron dendrites (Kole et al 2006)
kfast.mod
kslow.mod
nap.mod
nat.mod
SlowCa.mod
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