Prob. Inference of Short-Term Synaptic Plasticity in Neocort. Microcircuits (Costa et al. 2013)

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" ... As a solution (for Short Term Plasticity (STP) inference), we introduce a Bayesian formulation, which yields the posterior distribution over the model parameters given the data. First, we show that common STP protocols yield broad distributions over some model parameters. Using our result we propose a experimental protocol to more accurately determine synaptic dynamics parameters. Next, we infer the model parameters using experimental data from three different neocortical excitatory connection types. This reveals connection-specific distributions, which we use to classify synaptic dynamics. Our approach to demarcate connection-specific synaptic dynamics is an important improvement on the state of the art and reveals novel features from existing data."
1 . Costa RP, Sjöström PJ, van Rossum MC (2013) Probabilistic inference of short-term synaptic plasticity in neocortical microcircuits. Front Comput Neurosci 7:75 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Synapse;
Brain Region(s)/Organism:
Cell Type(s):
Gap Junctions:
Simulation Environment: MATLAB;
Model Concept(s): Short-term Synaptic Plasticity;
Implementer(s): Costa, Rui Ponte [ruipontecosta at];
%PDF2EPS  Convert a pdf file to eps format using pdftops
% Examples:
%   pdf2eps source dest
% This function converts a pdf file to eps format.
% This function requires that you have pdftops, from the Xpdf suite of
% functions, installed on your system. This can be downloaded from:
%   source - filename of the source pdf file to convert. The filename is
%            assumed to already have the extension ".pdf".
%   dest - filename of the destination eps file. The filename is assumed to
%          already have the extension ".eps".

% Copyright (C) Oliver Woodford 2009-2010

% Thanks to Aldebaro Klautau for reporting a bug when saving to
% non-existant directories.

function pdf2eps(source, dest)
% Construct the options string for pdftops
options = ['-q -paper match -eps -level2 "' source '" "' dest '"'];
% Convert to eps using pdftops
[status message] = pdftops(options);
% Check for error
if status
    % Report error
    if isempty(message)
        error('Unable to generate eps. Check destination directory is writable.');
% Fix the DSC error created by pdftops
fid = fopen(dest, 'r+');
if fid == -1
    % Cannot open the file
fgetl(fid); % Get the first line
str = fgetl(fid); % Get the second line
if strcmp(str(1:min(13, end)), '% Produced by')
    fseek(fid, -numel(str)-1, 'cof');
    fwrite(fid, '%'); % Turn ' ' into '%'