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Calcium waves and mGluR-dependent synaptic plasticity in CA1 pyr. neurons (Ashhad & Narayanan 2013)
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Accession:
150551
A morphologically realistic, conductance-based model equipped with kinetic schemes that govern several calcium signalling modules and pathways in CA1 pyramidal neurons
Reference:
1 .
Ashhad S, Narayanan R (2013) Quantitative interactions between the A-type K+ current and inositol trisphosphate receptors regulate intraneuronal Ca2+ waves and synaptic plasticity.
J Physiol
591
:1645-69
[
PubMed
]
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Model Information
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Model Type:
Neuron or other electrically excitable cell;
Synapse;
Channel/Receptor;
Dendrite;
Brain Region(s)/Organism:
Hippocampus;
Cell Type(s):
Hippocampus CA1 pyramidal GLU cell;
Channel(s):
I Na,t;
I L high threshold;
I T low threshold;
I A;
I K;
Ca pump;
Gap Junctions:
Receptor(s):
AMPA;
NMDA;
mGluR;
IP3;
Gene(s):
Transmitter(s):
Glutamate;
Simulation Environment:
NEURON;
Model Concept(s):
Active Dendrites;
Synaptic Plasticity;
Signaling pathways;
Calcium dynamics;
G-protein coupled;
Calcium waves;
Implementer(s):
Narayanan, Rishikesh [rishi at iisc.ac.in];
Ashhad, Sufyan [soofy at mbu.iisc.ernet.in];
Search NeuronDB
for information about:
Hippocampus CA1 pyramidal GLU cell
;
AMPA
;
NMDA
;
mGluR
;
IP3
;
I Na,t
;
I L high threshold
;
I T low threshold
;
I A
;
I K
;
Ca pump
;
Glutamate
;
/
AshhadNarayanan2013
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