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Sympathetic Preganglionic Neurone (Briant et al. 2014)
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Accession:
151482
A model of a sympathetic preganglionic neurone of muscle vasoconstrictor-type.
Reference:
1 .
Briant LJ, Stalbovskiy AO, Nolan MF, Champneys AR, Pickering AE (2014) Increased intrinsic excitability of muscle vasoconstrictor preganglionic neurons may contribute to the elevated sympathetic activity in hypertensive rats.
J Neurophysiol
112
:2756-78
[
PubMed
]
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Model Information
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Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Spinal cord lumbar motor neuron alpha ACh cell;
Spinal cord sympathetic preganglionic neuron;
Channel(s):
I Na,t;
I L high threshold;
I N;
I A;
I K;
I K,Ca;
I_AHP;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
MATLAB;
Model Concept(s):
Action Potential Initiation;
Activity Patterns;
Bursting;
Ion Channel Kinetics;
Temporal Pattern Generation;
Parameter Fitting;
Action Potentials;
Parameter sensitivity;
Implementer(s):
Search NeuronDB
for information about:
Spinal cord lumbar motor neuron alpha ACh cell
;
I Na,t
;
I L high threshold
;
I N
;
I A
;
I K
;
I K,Ca
;
I_AHP
;
/
SPN_ModelDB
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Fig. 3Ab
Fig. 3B