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Parvalbumin-positive basket cells differentiate among hippocampal pyramidal cells (Lee et al. 2014)
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This detailed microcircuit model explores the network level effects of sublayer specific connectivity in the mouse CA1. The differences in strengths and numbers of synapses between PV+ basket cells and either superficial sublayer or deep sublayer pyramidal cells enables a routing of inhibition from superficial to deep pyramidal cells. At the network level of this model, the effects become quite prominent when one compares the effect on firing rates when either the deep or superficial pyramidal cells receive a selective increase in excitation.
Lee SH, Marchionni I, Bezaire M, Varga C, Danielson N, Lovett-Barron M, Losonczy A, Soltesz I (2014) Parvalbumin-positive basket cells differentiate among hippocampal pyramidal cells.
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Hippocampus CA1 pyramidal GLU cell;
Hippocampus CA1 basket cell;
Detailed Neuronal Models;
Bezaire, Marianne [mariannejcase at gmail.com];
for information about:
Hippocampus CA1 pyramidal GLU cell
Other models using class_ppspont.hoc:
Hippocampal CA1 NN with spontaneous theta, gamma: full scale & network clamp (Bezaire et al 2016)
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