Olfactory bulb microcircuits model with dual-layer inhibition (Gilra & Bhalla 2015)

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Accession:153574
A detailed network model of the dual-layer dendro-dendritic inhibitory microcircuits in the rat olfactory bulb comprising compartmental mitral, granule and PG cells developed by Aditya Gilra, Upinder S. Bhalla (2015). All cell morphologies and network connections are in NeuroML v1.8.0. PG and granule cell channels and synapses are also in NeuroML v1.8.0. Mitral cell channels and synapses are in native python.
Reference:
1 . Gilra A, Bhalla US (2015) Bulbar microcircuit model predicts connectivity and roles of interneurons in odor coding. PLoS One 10:e0098045 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Olfactory bulb;
Cell Type(s): Olfactory bulb main mitral GLU cell; Olfactory bulb main interneuron periglomerular GABA cell; Olfactory bulb main interneuron granule MC GABA cell;
Channel(s): I A; I h; I K,Ca; I Sodium; I Calcium; I Potassium;
Gap Junctions:
Receptor(s): AMPA; NMDA; Gaba;
Gene(s):
Transmitter(s): Gaba; Glutamate;
Simulation Environment: Python; MOOSE/PyMOOSE;
Model Concept(s): Sensory processing; Sensory coding; Markov-type model; Olfaction;
Implementer(s): Bhalla, Upinder S [bhalla at ncbs.res.in]; Gilra, Aditya [aditya_gilra -at- yahoo -period- com];
Search NeuronDB for information about:  Olfactory bulb main mitral GLU cell; Olfactory bulb main interneuron periglomerular GABA cell; Olfactory bulb main interneuron granule MC GABA cell; AMPA; NMDA; Gaba; I A; I h; I K,Ca; I Sodium; I Calcium; I Potassium; Gaba; Glutamate;
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olfactory-bulb-gilra-bhalla
cells
PG_nrn
readme.txt *
hpg.mod *
kamt.mod *
kdrmt.mod *
naxn.mod *
nmdanetOB.mod *
TCa_d.mod *
coeff-table.txt *
forfig3.hoc *
gc.hoc *
Level2.xml
mitral.hoc *
mitral_davison2007_neurml_L1.xml
mod_func.c
mosinit.hoc *
nrnmech.dll
PGsimple_aditya2010_neuroML_L1_L2.xml
PGTest_nrn.py
                            
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    name = "NeuroML Level 1 file exported from NEURON"
    lengthUnits="micron">

<meta:notes>author: Aditya Gilra adapted from Cleland and Sethupathy 2006.</meta:notes>

<cells>
  <cell name="PG">
    <meta:notes>Cell: periglomerular morphml written by hand by Aditya.</meta:notes>
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<!-- Section: dendrites -->
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      </segment>
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        <distal x="8" y="21" z="0" diameter="1"/>
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    </segments>
    <cables  xmlns="http://morphml.org/morphml/schema"> <!-- Changing namespace from neuroml to morphml-->
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      -->
      <cable id="0" name="soma"/>
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      <cable id="6" name="spinehead1"/>
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        <!-- Note: values of cond dens are different in NEURON and phy units-->
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        <bio:mechanism xmlns:bio='http://morphml.org/biophysics/schema' type='Ion Concentration' name='Ca_mit_conc'>
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          <bio:parameter name='depth' value='0.125'>
            <bio:group>spineheads</bio:group>
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</cells>
</neuroml>