Find models by
Find models for
Find models of
L5 PFC microcircuit used to study persistent activity (Papoutsi et al. 2014, 2013)
Download zip file
Help downloading and running models
Using a heavily constrained biophysical model of a L5 PFC microcircuit we investigate the mechanisms that underlie persistent activity emergence (ON) and termination (OFF) and search for the minimum network size required for expressing these states within physiological regimes.
Papoutsi A, Sidiropoulou K, Cutsuridis V, Poirazi P (2013) Induction and modulation of persistent activity in a layer V PFC microcircuit model.
Front Neural Circuits
Papoutsi A, Sidiropoulou K, Poirazi P (2014) Dendritic nonlinearities reduce network size requirements and mediate ON and OFF states of persistent activity in a PFC microcircuit model.
PLoS Comput Biol
(Click on a link to find other models with that property)
Neocortex L5/6 pyramidal GLU cell;
I L high threshold;
Papoutsi, Athanasia [athpapoutsi at gmail.com];
for information about:
Neocortex L5/6 pyramidal GLU cell
I L high threshold
File not selected
<- Select file from this column.