Interaction of leak and IMI conductance on the STG over broad temperature range (Stadele et al 2015)

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The ZIP file contains a Hodgkin-Huxley based circuit model and the simulation environment MadSim used to study the interaction of leak and IMI on the gastric mill network of the crab (Cancer borealis) as represented in (C. Städele, S. Heigele and W. Stein, 2015) MadSim, the simulation environment used for this study, is freeware and included in the package.
1 . Stein W, Straub O, Ausborn J, Mader W, Wolf H (2008) Motor pattern selection by combinatorial code of interneuronal pathways. J Comput Neurosci 25:543-61 [PubMed]
2 . Ausborn J, Stein W, Wolf H (2007) Frequency control of motor patterning by negative sensory feedback. J Neurosci 27:9319-28 [PubMed]
3 . Städele C, Heigele S, Stein W (2015) Neuromodulation to the Rescue: Compensation of Temperature-Induced Breakdown of Rhythmic Motor Patterns via Extrinsic Neuromodulatory Input. PLoS Biol 13:e1002265 [PubMed]
4 . Daur N, Diehl F, Mader W, Stein W (2012) The stomatogastric nervous system as a model for studying sensorimotor interactions in real-time closed-loop conditions. Front Comput Neurosci 6:13 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Stomatogastric ganglion;
Cell Type(s): Stomatogastric Ganglion (STG) Lateral Gastric (LG) cell;
Channel(s): I MI;
Gap Junctions:
Transmitter(s): CabTRP 1a;
Simulation Environment: MadSim;
Model Concept(s): Temporal Pattern Generation; Invertebrate; Neuromodulation;
Search NeuronDB for information about:  I MI; CabTRP 1a;
madSim 6.11
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	PURPOSE:	description of all parameters used in the file

	35 parameter


HH_NA_E			- equilibrium potential of sodium channel
HH_NA_G			- conductance of sodium channel
HH_K_E			- equilibrium potential of potassium channel
HH_K_G			- conductance of potassium channel
HH_Form_Alpha_M		- form parameter for gate variable m, alpha term
HH_AalphaM		- rate constant
HH_V0alphaM		- half maximum potential
HH_BalphaM		- step width
HH_Form_Beta_M		- form parameter for gate variable m, beta term
HH_AbetaM		- rate constant
HH_V0betaM		- half maximum potential
HH_BbetaM		- step width
HH_M_POWER		- power of gate variable m
HH_M_INITIAL		- initial value of gate variable m
HH_Form_Alpha_H		- form parameter for gate variable h, alpha term
HH_AalphaH		- rate constant
HH_V0alphaH		- half maximum potential
HH_BalphaH		- step width
HH_Form_Beta_H		- form parameter for gate variable h, beta term
HH_AbetaH		- rate constant
HH_V0betaH		- half maximum potential
HH_BbetaH		- step width
HH_H_POWER		- power of gate variable h
HH_H_INITIAL		- initial value of gate variable h
HH_Form_Alpha_N		- form parameter for gate variable n, alpha term
HH_AalphaN		- rate constant
HH_V0alphaN		- half maximum potential
HH_BalphaN		- step width
HH_Form_Beta_N		- form parameter for gate variable n, beta term
HH_AbetaN		- rate constant
HH_V0betaN		- half maximum potential
HH_BbetaN		- step width
HH_N_POWER		- power of gate variable n
HH_N_INITIAL		- initial value of gate variable n
HH_SPIKE_THRESHOLD	- spike threshold, used only for spike identification