The ZIP file contains a Hodgkin-Huxley based circuit model and the simulation environment MadSim used to study the interaction of leak and IMI on the gastric mill network of the crab (Cancer borealis) as represented in (C. Städele, S. Heigele and W. Stein, 2015)
MadSim, the simulation environment used for this study, is freeware and included in the package.
Stein W, Straub O, Ausborn J, Mader W, Wolf H (2008) Motor pattern selection by combinatorial code of interneuronal pathways. J Comput Neurosci 25:543-61 [PubMed]
Ausborn J, Stein W, Wolf H (2007) Frequency control of motor patterning by negative sensory feedback. J Neurosci 27:9319-28 [PubMed]
Städele C, Heigele S, Stein W (2015) Neuromodulation to the Rescue: Compensation of Temperature-Induced Breakdown of Rhythmic Motor Patterns via Extrinsic Neuromodulatory Input. PLoS Biol 13:e1002265 [PubMed]
Daur N, Diehl F, Mader W, Stein W (2012) The stomatogastric nervous system as a model for studying sensorimotor interactions in real-time closed-loop conditions. Front Comput Neurosci 6:13 [PubMed]