Find models by
Find models for
Find models of
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Download zip file
Help downloading and running models
" ... In this work, we develop and apply an automated, stepwise method for fitting a neuron model to data with fine spatial resolution, such as that achievable with voltage sensitive dyes (VSDs) and Ca2+ imaging. ... We apply our method to simulated data from layer 5 pyramidal cells (L5PCs) and construct a model with reduced neuronal morphology. We connect the reduced-morphology neurons into a network and validate against simulated data from a high-resolution L5PC network model. ..."
Hay E, Hill S, Schürmann F, Markram H, Segev I (2011) Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties.
PLoS Comput Biol
Hay E, Segev I (2015) Dendritic Excitability and Gain Control in Recurrent Cortical Microcircuits.
Mäki-Marttunen T, Halnes G, Devor A, Metzner C, Dale AM, Andreassen OA, Einevoll GT (2018) A stepwise neuron model fitting procedure designed for recordings with high spatial resolution: Application to layer 5 pyramidal cells.
J Neurosci Methods
(Click on a link to find other models with that property)
Neuron or other electrically excitable cell;
Neocortex L5/6 pyramidal GLU cell;
I L high threshold;
I T low threshold;
I A, slow;
NEURON (web link to model);
Maki-Marttunen, Tuomo [tuomomm at uio.no];
Metzner, Christoph [c.metzner at herts.ac.uk];
for information about:
Neocortex L5/6 pyramidal GLU cell
I L high threshold
I T low threshold
I A, slow
Other models using cell1.asc:
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer V pyramidal cell functions and schizophrenia genetics (Mäki-Marttunen et al 2019)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
Schiz.-linked gene effects on intrinsic single-neuron excitability (Maki-Marttunen et al. 2016)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
File not selected
<- Select file from this column.