Striatal Spiny Projection Neuron (SPN) plasticity rule (Jedrzejewska-Szmek et al 2016)

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Accession:189153

Reference:
1 . Jedrzejewska-Szmek J, Damodaran S, Dorman DB, Blackwell KT (2017) Calcium dynamics predict direction of synaptic plasticity in striatal spiny projection neurons. Eur J Neurosci 45:1044-1056 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s): AMPA; NMDA; GabaA;
Gene(s):
Transmitter(s): Glutamate;
Simulation Environment: GENESIS;
Model Concept(s): Calcium dynamics; Synaptic Plasticity;
Implementer(s): Jedrzejewska-Szmek, Joanna ; Damodaran, Sriraman ; Dorman, Daniel B ; Blackwell, Avrama [avrama at gmu.edu];
Search NeuronDB for information about:  GabaA; AMPA; NMDA; Glutamate;
//***************************		MS Model, Version 5.0	**********************
//*************************** 	      MScell.p 			**********************
//			Tom Sheehan tsheeha2@gmu.edu	thsheeha@vt.edu	703-538-836
//*****************************************************************************

*relative
*cartesian
*asymmetric
*lambda_warn

*set_global ELEAK -0.070
*set_global RA 4.0 
*set_global RM 8.7
//change Cm to account for no spines - make 3x higher?
*set_global CM 0.01  
*set_global EREST_ACT -0.085

*start_cell
*spherical
soma none 16.000 0 0 16.000

*cylindrical
primdend1 soma 20 0 0 2.5
primdend2 soma 20 0 0 2.5
primdend3 soma 20 0 0 2.5
primdend4 soma 20 0 0 2.5