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Dendritic L-type Ca currents in motoneurons (Carlin et al 2000)
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A component of recorded currents demonstrated kinetics consistent with a current originating at a site spatially segregated from the soma. In response to step commands this component was seen as a late-onset, low amplitude persistent current whilst in response to depolarizing-repolarizing ramp commands a low voltage clockwise current hysteresis was recorded. Simulations using a neuromorphic motoneuron model could reproduce these currents only if a noninactivating calcium conductance was placed in the dendritic compartments.
Carlin KP, Jones KE, Jiang Z, Jordan LM, Brownstone RM (2000) Dendritic L-type calcium currents in mouse spinal motoneurons: implications for bistability.
Eur J Neurosci
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Neuron or other electrically excitable cell;
I L high threshold;
Ion Channel Kinetics;
Influence of Dendritic Geometry;
Detailed Neuronal Models;
Jones, Kelvin E [KEJones at ualberta.ca];
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I L high threshold
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