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CA1 pyramidal neuron: integration of subthreshold inputs from PP and SC (Migliore 2003)
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Accession:
19696
The model shows how the experimentally observed increase in the dendritic density of Ih and IA could have a major role in constraining the temporal integration window for the main CA1 synaptic inputs.
Reference:
1 .
Migliore M (2003) On the integration of subthreshold inputs from Perforant Path and Schaffer Collaterals in hippocampal CA1 pyramidal neurons.
J Comput Neurosci
14
:185-92
[
PubMed
]
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Model Information
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Model Type:
Dendrite;
Brain Region(s)/Organism:
Cell Type(s):
Hippocampus CA1 pyramidal GLU cell;
Channel(s):
I Na,t;
I A;
I K;
I h;
Gap Junctions:
Receptor(s):
AMPA;
Gene(s):
Transmitter(s):
Glutamate;
Simulation Environment:
NEURON;
Model Concept(s):
Action Potential Initiation;
Coincidence Detection;
Active Dendrites;
Detailed Neuronal Models;
Implementer(s):
Migliore, Michele [Michele.Migliore at Yale.edu];
Search NeuronDB
for information about:
Hippocampus CA1 pyramidal GLU cell
;
AMPA
;
I Na,t
;
I A
;
I K
;
I h
;
Glutamate
;
/
sc-pp
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