Subiculum network model with dynamic chloride/potassium homeostasis (Buchin et al 2016)

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Accession:206365
This is the code implementing the single neuron and spiking neural network dynamics. The network has the dynamic ion concentrations of extracellular potassium and intracellular chloride. The code contains multiple parameter variations to study various mechanisms of the neural excitability in the context of chloride homeostasis.
Reference:
1 . Buchin A, Chizhov A, Huberfeld G, Miles R, Gutkin BS (2016) Reduced Efficacy of the KCC2 Cotransporter Promotes Epileptic Oscillations in a Subiculum Network Model. J Neurosci 36:11619-11633 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Synapse; Extracellular; Dendrite; Realistic Network; Glia;
Brain Region(s)/Organism: Hippocampus;
Cell Type(s): Hippocampus CA1 pyramidal GLU cell; Hodgkin-Huxley neuron; Hippocampus CA1 PV+ fast-firing interneuron;
Channel(s): KCC2; I Sodium; I Potassium; Na/K pump; I Calcium; I Chloride; I Cl, leak; I M; I Na, leak; I K,leak; I_HCO3; I Na,p;
Gap Junctions:
Receptor(s): NMDA; AMPA; GabaA;
Gene(s):
Transmitter(s): Ions; Gaba; Glutamate;
Simulation Environment: MATLAB; XPPAUT;
Model Concept(s): Bursting; Epilepsy; Chloride regulation; Activity Patterns; Oscillations; Homeostasis; Potassium buffering; Brain Rhythms; Extracellular Fields;
Implementer(s): Buchin, Anatoly [anat.buchin at gmail.com];
Search NeuronDB for information about:  Hippocampus CA1 pyramidal GLU cell; GabaA; AMPA; NMDA; I Chloride; I Na,p; I K,leak; I M; I Sodium; I Calcium; I Potassium; Na/K pump; I Cl, leak; I Na, leak; KCC2; I_HCO3; Gaba; Glutamate; Ions;
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BuchinEtAl2016KCC2
.git
hooks
applypatch-msg.sample *
commit-msg.sample *
post-update.sample *
pre-applypatch.sample *
pre-commit.sample *
prepare-commit-msg.sample *
pre-push.sample *
pre-rebase.sample *
update.sample *
                            
#!/bin/sh

# An example hook script to verify what is about to be pushed.  Called by "git
# push" after it has checked the remote status, but before anything has been
# pushed.  If this script exits with a non-zero status nothing will be pushed.
#
# This hook is called with the following parameters:
#
# $1 -- Name of the remote to which the push is being done
# $2 -- URL to which the push is being done
#
# If pushing without using a named remote those arguments will be equal.
#
# Information about the commits which are being pushed is supplied as lines to
# the standard input in the form:
#
#   <local ref> <local sha1> <remote ref> <remote sha1>
#
# This sample shows how to prevent push of commits where the log message starts
# with "WIP" (work in progress).

remote="$1"
url="$2"

z40=0000000000000000000000000000000000000000

while read local_ref local_sha remote_ref remote_sha
do
	if [ "$local_sha" = $z40 ]
	then
		# Handle delete
		:
	else
		if [ "$remote_sha" = $z40 ]
		then
			# New branch, examine all commits
			range="$local_sha"
		else
			# Update to existing branch, examine new commits
			range="$remote_sha..$local_sha"
		fi

		# Check for WIP commit
		commit=`git rev-list -n 1 --grep '^WIP' "$range"`
		if [ -n "$commit" ]
		then
			echo >&2 "Found WIP commit in $local_ref, not pushing"
			exit 1
		fi
	fi
done

exit 0