Find models by
Find models for
Find models of
Hippocampus CA1 pyramidal model with Na channel exhibiting slow inactivation (Menon et al. 2009)
Download zip file
Help downloading and running models
These NEURON simulations show the effect of prolonged inactivation of sodium channels on attenuation of trains of backpropagating action potentials (bAPs). The new sodium channel model is a Markov model derived using a state-mutating genetic algorithm, as described in the paper.
Menon V, Spruston N, Kath WL (2009) A state-mutating genetic algorithm to design ion-channel models.
Proc Natl Acad Sci U S A
(Click on a link to find other models with that property)
Neuron or other electrically excitable cell;
Hippocampus CA1 pyramidal GLU cell;
I Na, slow inactivation;
Ion Channel Kinetics;
Menon, Vilas [vilasmenon2008 at u dot northwestern dot edu];
for information about:
Hippocampus CA1 pyramidal GLU cell
I Na, slow inactivation
File not selected
<- Select file from this column.