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Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
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Model Information
Model File
Accession:
223649
" ... We hypothesized that currents are grouped into distinct modules that shape specific neuronal characteristics or signatures, such as resting potential, sub-threshold oscillations, and spiking waveforms, for several classes of neurons. For such a grouping to occur, the currents within one module should have minimal functional interference with currents belonging to other modules. This condition is satisfied if the gating functions of currents in the same module are grouped together on the voltage axis; in contrast, such functions are segregated along the voltage axis for currents belonging to different modules. We tested this hypothesis using four published example case models and found it to be valid for these classes of neurons. ..."
Reference:
1 .
Alturki A, Feng F, Nair A, Guntu V, Nair SS (2016) Distinct current modules shape cellular dynamics in model neurons.
Neuroscience
334
:309-331
[
PubMed
]
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Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Hippocampus;
Amygdala;
Cell Type(s):
Abstract single compartment conductance based cell;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Simplified Models;
Activity Patterns;
Oscillations;
Methods;
Olfaction;
Implementer(s):
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AlturkiEtAl2016
2_Pospischil
Segregated
cadecay_destexhe.mod
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Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
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HH_traub.mod
IL_gutnick.mod
IM_cortex.mod
IT_huguenard.mod
demo_IN_FS.hoc
*
Other models using demo_IN_FS.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
demo_PY_IB.hoc
*
Other models using demo_PY_IB.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
demo_PY_IBR.hoc
*
Other models using demo_PY_IBR.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
demo_PY_LTS.hoc
*
Other models using demo_PY_LTS.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
demo_PY_RS.hoc
*
Other models using demo_PY_RS.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
mosinit.hoc
*
Other models using mosinit.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
rundemo.hoc
*
Other models using rundemo.hoc:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
sIN_template
*
Other models using sIN_template:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
sPY_template
*
Other models using sPY_template:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
sPYb_template
*
Other models using sPYb_template:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
sPYbr_template
*
Other models using sPYbr_template:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
sPYr_template
*
Other models using sPYr_template:
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
load_file("nrngui.hoc") load_file("rundemo.hoc") print "Select a cell then press Init & Run button"
