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Impedance spectrum in cortical tissue: implications for LFP signal propagation (Miceli et al. 2017)
 
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Model Information
Model File
Accession:
224923
" ... Here, we performed a detailed investigation of the frequency dependence of the conductivity within cortical tissue at microscopic distances using small current amplitudes within the typical (neuro)physiological micrometer and sub-nanoampere range. We investigated the propagation of LFPs, induced by extracellular electrical current injections via patch-pipettes, in acute rat brain slice preparations containing the somatosensory cortex in vitro using multielectrode arrays. Based on our data, we determined the cortical tissue conductivity over a 100-fold increase in signal frequency (5-500 Hz). Our results imply at most very weak frequency-dependent effects within the frequency range of physiological LFPs. Using biophysical modeling, we estimated the impact of different putative impedance spectra. Our results indicate that frequency dependencies of the order measured here and in most other studies have negligible impact on the typical analysis and modeling of LFP signals from extracellular brain recordings."
Reference:
1 .
Miceli S, Ness TV, Einevoll GT, Schubert D (2017) Impedance Spectrum in Cortical Tissue: Implications for Propagation of LFP Signals on the Microscopic Level
Eneuro
4
:1-15
Citations
Citation Browser
Model Information
(Click on a link to find other models with that property)
Model Type:
Extracellular;
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Neocortex L5/6 pyramidal GLU cell;
Channel(s):
I Na,p;
I Na,t;
I L high threshold;
I A;
I h;
I K,Ca;
I Calcium;
I A, slow;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
Python;
NEURON;
Model Concept(s):
Extracellular Fields;
Methods;
Simplified Models;
Detailed Neuronal Models;
Implementer(s):
Search NeuronDB
for information about:
Neocortex L5/6 pyramidal GLU cell
;
I Na,p
;
I Na,t
;
I L high threshold
;
I A
;
I h
;
I K,Ca
;
I Calcium
;
I A, slow
;
/
tissue_impedance_impact
hay
sim_results
ampa.mod
Ca_HVA.mod
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Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
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L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
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Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Preserving axosomatic spiking features despite diverse dendritic morphology (Hay et al., 2013)
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Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Human Cortical L5 Pyramidal Cell (Rich et al. 2021)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
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*
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Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
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Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
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Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
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Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Cortical Layer 5b pyr. cell with [Na+]i mechanisms, from Hay et al 2011 (Zylbertal et al 2017)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
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Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
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Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
epsp.mod
*
Other models using epsp.mod:
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Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
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Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
Schiz.-linked gene effects on intrinsic single-neuron excitability (Maki-Marttunen et al. 2016)
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glutamate.mod
Ih.mod
*
Other models using Ih.mod:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
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Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
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Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
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Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Cortical Layer 5b pyr. cell with [Na+]i mechanisms, from Hay et al 2011 (Zylbertal et al 2017)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
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Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
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Mirror Neuron (Antunes et al 2017)
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SCN1A gain-of-function in early infantile encephalopathy (Berecki et al 2019)
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Im.mod
*
Other models using Im.mod:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
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Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Cortical Layer 5b pyr. cell with [Na+]i mechanisms, from Hay et al 2011 (Zylbertal et al 2017)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Human Cortical L5 Pyramidal Cell (Rich et al. 2021)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
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Layer 5 Pyramidal Neuron (Shai et al., 2015)
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SCN1A gain-of-function in early infantile encephalopathy (Berecki et al 2019)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
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K_Pst.mod
*
Other models using K_Pst.mod:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
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Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Cortical Layer 5b pyr. cell with [Na+]i mechanisms, from Hay et al 2011 (Zylbertal et al 2017)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Mirror Neuron (Antunes et al 2017)
Preserving axosomatic spiking features despite diverse dendritic morphology (Hay et al., 2013)
SCN1A gain-of-function in early infantile encephalopathy (Berecki et al 2019)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
K_Tst.mod
*
Other models using K_Tst.mod:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Cortical Layer 5b pyr. cell with [Na+]i mechanisms, from Hay et al 2011 (Zylbertal et al 2017)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Human Cortical L5 Pyramidal Cell (Rich et al. 2021)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Mirror Neuron (Antunes et al 2017)
Preserving axosomatic spiking features despite diverse dendritic morphology (Hay et al., 2013)
SCN1A gain-of-function in early infantile encephalopathy (Berecki et al 2019)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
Nap_Et2.mod
NaTa_t.mod
*
Other models using NaTa_t.mod:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Cortical Layer 5b pyr. cell with [Na+]i mechanisms, from Hay et al 2011 (Zylbertal et al 2017)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Mirror Neuron (Antunes et al 2017)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
NaTs2_t.mod
siniclamp.mod
SK_E2.mod
*
Other models using SK_E2.mod:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Cortical Layer 5b pyr. cell with [Na+]i mechanisms, from Hay et al 2011 (Zylbertal et al 2017)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Human Cortical L5 Pyramidal Cell (Rich et al. 2021)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Mirror Neuron (Antunes et al 2017)
Preserving axosomatic spiking features despite diverse dendritic morphology (Hay et al., 2013)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
SKv3_1.mod
*
Other models using SKv3_1.mod:
Cortical Layer 5b pyr. cell with [Na+]i mechanisms, from Hay et al 2011 (Zylbertal et al 2017)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Preserving axosomatic spiking features despite diverse dendritic morphology (Hay et al., 2013)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
stim.mod
cell1.hoc
cell1.rot
custom_codes.hoc
hay_active_declarations.py
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