MicrocircuitDB: CA1 pyr cell: Inhibitory modulation of spatial selectivity+phase precession (Grienberger et al 2017)

CA1 pyr cell: Inhibitory modulation of spatial selectivity+phase precession (Grienberger et al 2017)

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Accession:225080

Spatially uniform synaptic inhibition enhances spatial selectivity and temporal coding in CA1 place cells by suppressing broad out-of-field excitation.
Reference:
1 . Grienberger C, Milstein AD, Bittner KC, Romani S, Magee JC (2017) Inhibitory suppression of heterogeneously tuned excitation enhances spatial coding in CA1 place cells. Nat Neurosci 20:417-426 [PubMed]

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Model Information (Click on a link to find other models with that property)

Model Type:	Neuron or other electrically excitable cell; Realistic Network;
Brain Region(s)/Organism:	Hippocampus;
Cell Type(s):	Hippocampus CA1 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s):	NMDA;
Gene(s):
Transmitter(s):
Simulation Environment:	NEURON; Python;
Model Concept(s):	Active Dendrites; Detailed Neuronal Models; Place cell/field; Synaptic Integration; Short-term Synaptic Plasticity; Spatial Navigation; Feature selectivity;
Implementer(s):	Milstein, Aaron D. [aaronmil at stanford.edu];

Search NeuronDB for information about: Hippocampus CA1 pyramidal GLU cell; NMDA;

GrienbergerEtAl2017

exp2EPSG_NMDA.mod

gaba_a_kin.mod *

nmda_kin5.mod *

batch_EPSP_attenuation.sh

batch_place_cell_r_inp.sh

batch_place_cell_record_i_syn.sh

batch_place_cell_single_compartment.sh

batch_place_cell_subtr_inh.sh

batch_place_cell_subtr_inh_shifted.sh

batch_place_cell_subtr_inh_vclamp.sh

batch_process_i_syn_files.sh

batch_spine_attenuation_ratio.sh

build_expected_EPSP_reference.sh

build_expected_EPSP_reference_controller.py

build_expected_EPSP_reference_engine.py

consolidate_i_syn_files.py

consolidate_tracked_spine_data.py

fit_parameter_exponential_distribution.py

function_lib.py

optimize_AMPA_KIN.py

optimize_dendritic_excitability_020416.py

optimize_GABA_A_KIN.py

optimize_NMDA_KIN2.py

parallel_branch_cooperativity.sh

parallel_branch_cooperativity_no_nmda.sh

parallel_clustered_branch_cooperativity_nmda_controller_110315.py

parallel_clustered_branch_cooperativity_nmda_engine_110315.py

parallel_EPSP_attenuation_controller.py

parallel_EPSP_attenuation_engine.py

parallel_EPSP_i_attenuation_controller.py

parallel_EPSP_i_attenuation_engine.py

parallel_expected_EPSP_controller.py

parallel_expected_EPSP_engine.py

parallel_optimize_branch_cooperativity.sh

parallel_optimize_branch_cooperativity_nmda_kin3_controller.py

parallel_optimize_branch_cooperativity_nmda_kin3_engine.py

parallel_optimize_EPSP_amp_controller.py

parallel_optimize_EPSP_amp_engine.py

parallel_optimize_pr.sh

parallel_optimize_pr_controller_020116.py

parallel_optimize_pr_engine_020116.py

parallel_rinp_controller.py

parallel_rinp_engine.py

parallel_spine_attenuation_ratio_controller.py

parallel_spine_attenuation_ratio_engine.py

plot_channel_distributions.py

plot_NMDAR_kinetics.py

plot_results.py

plot_spine_traces.py

plot_synaptic_conductance_facilitation.py

process_i_syn_files.py

record_bAP_attenuation.py

simulate_place_cell_no_precession.py

simulate_place_cell_single_compartment.py

simulate_place_cell_single_compartment_no_nmda.py

simulate_place_cell_subtr_inh.py

simulate_place_cell_subtr_inh_add_noise.py

simulate_place_cell_subtr_inh_add_noise_no_na.py

simulate_place_cell_subtr_inh_no_na.py

simulate_place_cell_subtr_inh_no_nmda_no_na.py

simulate_place_cell_subtr_inh_r_inp.py

simulate_place_cell_subtr_inh_rec_i_syn.py

simulate_place_cell_subtr_inh_shifted.py

simulate_place_cell_subtr_inh_silent.py

simulate_place_cell_subtr_inh_vclamp.py

specify_cells.py

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