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Cortical Layer 5b pyr. cell with [Na+]i mechanisms, from Hay et al 2011 (Zylbertal et al 2017)
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Accession:
230326
" ... Based on a large body of experimental recordings from both the soma and dendrites of L5b pyramidal cells in adult rats, we characterized key features of the somatic and dendritic firing and quantified their statistics. We used these features to constrain the density of a set of ion channels over the soma and dendritic surface via multi-objective optimization with an evolutionary algorithm, thus generating a set of detailed conductance-based models that faithfully replicate the back-propagating action potential activated Ca(2+) spike firing and the perisomatic firing response to current steps, as well as the experimental variability of the properties. Furthermore, we show a useful way to analyze model parameters with our sets of models, which enabled us to identify some of the mechanisms responsible for the dynamic properties of L5b pyramidal cells as well as mechanisms that are sensitive to morphological changes. ..."
Reference:
1 .
Hay E, Hill S, Schürmann F, Markram H, Segev I (2011) Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties.
PLoS Comput Biol
7
:e1002107
[
PubMed
]
2 .
Zylbertal A, Yarom Y, Wagner S (2017) The Slow Dynamics of Intracellular Sodium Concentration Increase the Time Window of Neuronal Integration: A Simulation Study
Front. Comput. Neurosci.
11(85)
:1-16
[
PubMed
]
Citations
Citation Browser
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Neocortex;
Cell Type(s):
Neocortex L5/6 pyramidal GLU cell;
Channel(s):
Na/Ca exchanger;
Na/K pump;
I Sodium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Dendritic Action Potentials;
Detailed Neuronal Models;
Action Potentials;
Reaction-diffusion;
Synaptic Plasticity;
Active Dendrites;
Olfaction;
Implementer(s):
Zylbertal, Asaph [asaph.zylbertal at mail.huji.ac.il];
Search NeuronDB
for information about:
Neocortex L5/6 pyramidal GLU cell
;
I Sodium
;
Na/Ca exchanger
;
Na/K pump
;
/
L5PC_converted
mod
Ca_HVA.mod
Ca_LVAst.mod
cadp.mod
CaDynamics_E2.mod
*
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Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
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Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Human Cortical L5 Pyramidal Cell (Rich et al. 2021)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Impedance spectrum in cortical tissue: implications for LFP signal propagation (Miceli et al. 2017)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Mirror Neuron (Antunes et al 2017)
Preserving axosomatic spiking features despite diverse dendritic morphology (Hay et al., 2013)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
Ih.mod
*
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Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
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Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
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Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Impedance spectrum in cortical tissue: implications for LFP signal propagation (Miceli et al. 2017)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Mirror Neuron (Antunes et al 2017)
Preserving axosomatic spiking features despite diverse dendritic morphology (Hay et al., 2013)
SCN1A gain-of-function in early infantile encephalopathy (Berecki et al 2019)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
Im.mod
*
Other models using Im.mod:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
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Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
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Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Human Cortical L5 Pyramidal Cell (Rich et al. 2021)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Impedance spectrum in cortical tissue: implications for LFP signal propagation (Miceli et al. 2017)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Mirror Neuron (Antunes et al 2017)
SCN1A gain-of-function in early infantile encephalopathy (Berecki et al 2019)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
K_Pst.mod
*
Other models using K_Pst.mod:
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Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
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Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
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Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Impedance spectrum in cortical tissue: implications for LFP signal propagation (Miceli et al. 2017)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Mirror Neuron (Antunes et al 2017)
Preserving axosomatic spiking features despite diverse dendritic morphology (Hay et al., 2013)
SCN1A gain-of-function in early infantile encephalopathy (Berecki et al 2019)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
K_Tst.mod
*
Other models using K_Tst.mod:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Human Cortical L5 Pyramidal Cell (Rich et al. 2021)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Impedance spectrum in cortical tissue: implications for LFP signal propagation (Miceli et al. 2017)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Mirror Neuron (Antunes et al 2017)
Preserving axosomatic spiking features despite diverse dendritic morphology (Hay et al., 2013)
SCN1A gain-of-function in early infantile encephalopathy (Berecki et al 2019)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
nadp.mod
Nap_Et2.mod
*
Other models using Nap_Et2.mod:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Mirror Neuron (Antunes et al 2017)
Preserving axosomatic spiking features despite diverse dendritic morphology (Hay et al., 2013)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
naSyn.mod
NaTa_t.mod
*
Other models using NaTa_t.mod:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Impedance spectrum in cortical tissue: implications for LFP signal propagation (Miceli et al. 2017)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Mirror Neuron (Antunes et al 2017)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
NaTs2_t.mod
*
Other models using NaTs2_t.mod:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Human Cortical L5 Pyramidal Cell (Rich et al. 2021)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Mirror Neuron (Antunes et al 2017)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
ncx.mod
SK_E2.mod
*
Other models using SK_E2.mod:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Human Cortical L5 Pyramidal Cell (Rich et al. 2021)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al accepted)
Impedance spectrum in cortical tissue: implications for LFP signal propagation (Miceli et al. 2017)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Mice Somatosensory L2/3 Pyramidal cells (Iascone et al 2020)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Mirror Neuron (Antunes et al 2017)
Preserving axosomatic spiking features despite diverse dendritic morphology (Hay et al., 2013)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
SKv3_1.mod
*
Other models using SKv3_1.mod:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Effect of ionic diffusion on extracellular potentials (Halnes et al 2016)
Four-pathway phenomenological synaptic plasticity model (Ebner et al. 2019)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Impedance spectrum in cortical tissue: implications for LFP signal propagation (Miceli et al. 2017)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
Preserving axosomatic spiking features despite diverse dendritic morphology (Hay et al., 2013)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Shaping NMDA spikes by timed synaptic inhibition on L5PC (Doron et al. 2017)
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