MicrocircuitDB: The cannula artifact (Chandler & Hodgkin 1965)

The cannula artifact (Chandler & Hodgkin 1965)

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Accession:230888

Chandler and Hodgkin 1965 describes how using a high impedance electrode can lead to squid axon recordings that appear to overshoot the sodium reversal potential, thus resolving controversial recordings at the time.
Reference:
1 . Chandler WK, Hodgkin AL (1965) The effect of internal sodium on the action potential in the presence of different internal anions. J Physiol 181:594-611 [PubMed]

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Model Information (Click on a link to find other models with that property)

Model Type:	Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):	Squid axon;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:	NEURON;
Model Concept(s):	Methods; Action Potentials; Tutorial/Teaching;
Implementer(s):	Hines, Michael [Michael.Hines at Yale.edu];

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