Advanced search
User account
Login
Register
Find models by
Model name
First author
Each author
Find models for
Brain region
Concept
Find models of
Realistic Microcircuits
Connectionist Networks
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Download zip file
Auto-launch
Help downloading and running models
Model Information
Model File
Accession:
236310
This model achieves electrotonic transform and computes mean inward and outward attenuation from 0 to 500 Hz input; and randomly activates synapses along dendrites to simulate AMPAR mediated EPSCs. For electrotonic analysis, in Elec folder, the entry file is MSNelec_transform.hoc. For EPSC simulation, in Syn folder, the entry file is randomepsc.hoc. Run read_EPSCsims_mdb_alone.m next with the simulated parameter values specified to compute the mean EPSC.
Reference:
1 .
Goodliffe JW, Song H, Rubakovic A, Chang W, Medalla M, Weaver CM, Luebke JI (2018) Differential changes to D1 and D2 medium spiny neurons in the 12-month-old Q175+/- mouse model of Huntington's Disease.
PLoS One
13
:e0200626
[
PubMed
]
Citations
Citation Browser
Model Information
(Click on a link to find other models with that property)
Model Type:
Synapse;
Brain Region(s)/Organism:
Striatum;
Cell Type(s):
Neostriatum spiny neuron;
Channel(s):
Gap Junctions:
Receptor(s):
AMPA;
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Detailed Neuronal Models;
Membrane Properties;
Electrotonus;
Synaptic-input statistic;
Huntington's;
Implementer(s):
Search NeuronDB
for information about:
AMPA
;
/
GoodliffeEtAl2018
Elec
tau_tables
kir.mod
*
Other models using kir.mod:
A model of optimal learning with redundant synaptic connections (Hiratani & Fukai 2018)
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Dendritic Discrimination of Temporal Input Sequences (Branco et al. 2010)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
actionPotentialPlayer.hoc
*
Other models using actionPotentialPlayer.hoc:
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Rhesus Monkey Layer 3 Pyramidal Neurons: V1 vs PFC (Amatrudo, Weaver et al. 2012)
all_tau_vecs.hoc
analyticFunctions.hoc
*
Other models using analyticFunctions.hoc:
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Rhesus Monkey Layer 3 Pyramidal Neurons: V1 vs PFC (Amatrudo, Weaver et al. 2012)
aux_procs.hoc
baseline_values.txt
basic_procs.hoc
colorDendrites.hoc
electro_procs.hoc
*
Other models using electro_procs.hoc:
Rhesus Monkey Layer 3 Pyramidal Neurons: V1 vs PFC (Amatrudo, Weaver et al. 2012)
fixnseg.hoc
*
Other models using fixnseg.hoc:
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Rhesus Monkey Layer 3 Pyramidal Neurons: V1 vs PFC (Amatrudo, Weaver et al. 2012)
load_scripts.hoc
*
Other models using load_scripts.hoc:
Rhesus Monkey Layer 3 Pyramidal Neurons: V1 vs PFC (Amatrudo, Weaver et al. 2012)
measureMeanAtten.hoc
MSN_fixDiams.hoc
MSNelect.hoc
MSNelect_transform.hoc
Nov3IR3a.hoc
Nov9IR2a_spine.hoc
readcell.hoc
File not selected
<- Select file from this column.
