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Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
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Model Information
Model File
Accession:
236310
This model achieves electrotonic transform and computes mean inward and outward attenuation from 0 to 500 Hz input; and randomly activates synapses along dendrites to simulate AMPAR mediated EPSCs. For electrotonic analysis, in Elec folder, the entry file is MSNelec_transform.hoc. For EPSC simulation, in Syn folder, the entry file is randomepsc.hoc. Run read_EPSCsims_mdb_alone.m next with the simulated parameter values specified to compute the mean EPSC.
Reference:
1 .
Goodliffe JW, Song H, Rubakovic A, Chang W, Medalla M, Weaver CM, Luebke JI (2018) Differential changes to D1 and D2 medium spiny neurons in the 12-month-old Q175+/- mouse model of Huntington's Disease.
PLoS One
13
:e0200626
[
PubMed
]
Citations
Citation Browser
Model Information
(Click on a link to find other models with that property)
Model Type:
Synapse;
Brain Region(s)/Organism:
Striatum;
Cell Type(s):
Neostriatum spiny neuron;
Channel(s):
Gap Junctions:
Receptor(s):
AMPA;
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Detailed Neuronal Models;
Membrane Properties;
Electrotonus;
Synaptic-input statistic;
Huntington's;
Implementer(s):
Search NeuronDB
for information about:
AMPA
;
Download the displayed file
/
GoodliffeEtAl2018
Elec
tau_tables
tauh_car.txt
*
Other models using tauh_car.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
tauh_cat.txt
*
Other models using tauh_cat.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
tauh_kas.txt
*
Other models using tauh_kas.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
tauh_krp.txt
*
Other models using tauh_krp.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
tauh_naf.txt
*
Other models using tauh_naf.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
tauh_nap.txt
*
Other models using tauh_nap.txt:
A Fast Rhythmic Bursting Cell: in vivo cell modeling (Lee 2007)
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
taum_cat.txt
*
Other models using taum_cat.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
taum_kaf.txt
*
Other models using taum_kaf.txt:
A Fast Rhythmic Bursting Cell: in vivo cell modeling (Lee 2007)
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
taum_kas.txt
*
Other models using taum_kas.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
taum_kir.txt
*
Other models using taum_kir.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
taum_krp.txt
*
Other models using taum_krp.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
taum_naf.txt
*
Other models using taum_naf.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
vtau_car.txt
*
Other models using vtau_car.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
vtau_cat.txt
*
Other models using vtau_cat.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
vtau_kaf.txt
*
Other models using vtau_kaf.txt:
A Fast Rhythmic Bursting Cell: in vivo cell modeling (Lee 2007)
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
vtau_kas.txt
*
Other models using vtau_kas.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
vtau_kir.txt
*
Other models using vtau_kir.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
vtau_krp.txt
*
Other models using vtau_krp.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
vtau_naf.txt
*
Other models using vtau_naf.txt:
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
vtau_nap.txt
*
Other models using vtau_nap.txt:
A Fast Rhythmic Bursting Cell: in vivo cell modeling (Lee 2007)
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Calcium response prediction in the striatal spines depending on input timing (Nakano et al. 2013)
Electrotonic transform and EPSCs for WT and Q175+/- spiny projection neurons (Goodliffe et al 2018)
Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
NAcc medium spiny neuron: effects of cannabinoid withdrawal (Spiga et al. 2010)
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