//SimParams.g
//*************** Parameters to control model (p file, spinesYesNo) and simulations
str neuronname = "/cell"
str pfile="MScell/MScelltaperspines.p" //"MScell/MScellTest.p" //
float outputclock=1e-4 //output time step (Sec)
float simdt=5e-6 // Simulation time step (Second)
int spinesYesNo=1
int synYesNo=1
str DA="UI"
str whichSpines = "1,2,3"
float initSim = 0.9
int TooFast = 30 //what is the frequency that results in depletion of synaptic vesicles
//Parameters for learning rule
int plastYesNo = 0
float post_thresh_hi = .46e-3 //0.5
float post_thresh_lo = 0.2e-3 //0.2
float dur_hi = 2.e-3 //
float dur_lo = .032 //0.2
//whether to elicit and single pulses before and after plasticity protocol
int pulseYN=0
int desensYesNo=0
str facchan="/cell/desens"
int GABAYesNo = 0
// phasic GABA switch
int GABAtonic = 0//tonic GABA switch
str GABAstim = "tertdend1_1"
//Parameters for current injection for IV/IF curves
str input_name = "spine_stim"
str GABA_input = "GABA_stim"
float SMALLNUMBER=1e-15
str precell="/othercell"
//Parameters for current injection for IV/IF curves
str injectName="/injectCurr"
float injectstart=-300e-12 //1e-9
float inc=100e-12 //20e-12
float delay=0.1
float duration=0.25 //0.005
int numcurr=7
float basal_current=0
float basal_current_inj = 0
//parameters for current injection to produce AP during upstate or STDP
float upstate_time = 0.3
float AP_durtime = 0.005 //duration of AP depolarization at soma, 5 ms
//parameters for synaptic stimulation
int tertdendstart=1
int tertdendsegstart=1
str stimcomp
str multispinefile
str multispinehead
//output files. Xfile is name of ascii object and suffix for filename
//Xhead is the header written to the file
//Vm output is required, Gk and Ca are optional
str Vmfile="Vm"
str Vmhead
int CaOut=1
str Cafile
str Cahead
int GkOut=1
str Gkfile
str Gkhead
str Ikfile
str Ikhead
str multispinefile
str multispinehead
str spinefile
str spinehead
str presynfile
int somainjout = 0
str somainjfile = "somaInj"
//list of compartments, channels and calcium objects for output, comma separated
str comps="soma,primdend1,secdend11,tertdend1_1,tertdend1_2,tertdend1_3,tertdend1_4,tertdend1_5,tertdend1_6,tertdend1_7" //These should include comps of stim spines to see NMDA
str chans="CaL13_channel,CaL12_channel,CaR_channel,CaT32_channel,CaT33_channel" //"X" if no channels.
//these must match the calcium type, i.e. pools for type 1 and CaMN, etc for type 0
str CaBufs="CaMN,CaMC,calbindin,FixedBuffer"//"Ca_pool_LT,Ca_pool_NR,Ca_pool_all,Ca_pool_nmda" // X = just calcium, no buffers
//***********input rates for Glutamate, and durations when doing a gradient.
//most of these values should be passed in as parameters or declared in SimParams
//make the secondRate and thirdRate = first rate when second_time and third_time = 0
//*rates used for gradient and flat inputs, multiply by 10
//18: high=*50, med=*3, low=*1, gaba=*7
//19: high=*40, med=*5, low=*2, gaba=*7
//flat: rate=*4 gaba=*7
float first_time = 0.01
float second_time = 0.2
int Rate1
int Rate2
int Rate3
int GabaRate=70
create table APtime
int xmax=7
call APtime TABCREATE 7 0 7
setfield APtime table->table[0] 0.005 \
table->table[1] 0.010 \
table->table[2] 0.020 \
table->table[3] 0.030 \
table->table[4] 0.050 \
table->table[5] 0.100 \
table->table[6] 0.175 \
table->table[7] 0.290
//From STDP files:
//1: high=*50, med =*1, low =/1.5, gaba = *2
//2: high=*40, med =*1, low =/1.5, gaba = *2
//3: high=*40, med =*1, low =/1.5, gaba = *3
//*****4: high=*40, med =*1, low =/1.5, gaba = *4
//5: high=*60, med =/2, low =/5, gaba = *4
//6: high=*30, med =*1, low =/1.5, gaba = *4
/* Three variations for stimulation in PlasStim
a. PreStim=0 indicates stimulate a single compartment,
second parameter must be name of compartment
b. PreStim between 0 and 1.0 indicates stimulate a percentage
of glutamate synapses. The PreStim value is treated as percent.
in this case, StimComp should be either
b1. "any", meaning stimulate a percentage of _any_ compartments, or
b2. a value indicating minimum distance from soma for stimulation.
of course, setting a value = 0 is the same as "any"
Same variations plus one more for stimulation in STDP
If PreStim <= 0, no stim, only AP*/