Advanced search
User account
Login
Register
Find models by
Model name
First author
Each author
Find models for
Brain region
Concept
Find models of
Realistic Microcircuits
Connectionist Networks
Layer V pyramidal cell functions and schizophrenia genetics (Mäki-Marttunen et al 2019)
Download zip file
Auto-launch
Help downloading and running models
Model Information
Model File
Versions
Accession:
249463
Study on how GWAS-identified risk genes of shizophrenia affect excitability and integration of inputs in thick-tufted layer V pyramidal cells
Reference:
1 .
Mäki-Marttunen T, Devor A, Phillips WA, Dale AM, Andreassen OA, Einevoll GT (2019) Computational modeling of genetic contributions to excitability and neural coding in layer V pyramidal cells: applications to schizophrenia pathology
Front. Comput. Neurosci.
13
:66
Citations
Citation Browser
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Neocortex;
Cell Type(s):
Channel(s):
I A;
I M;
I h;
I K,Ca;
I Calcium;
I A, slow;
I Na,t;
I Na,p;
I L high threshold;
I T low threshold;
Gap Junctions:
Receptor(s):
AMPA;
NMDA;
Gaba;
Gene(s):
Transmitter(s):
Glutamate;
Gaba;
Simulation Environment:
NEURON;
Python;
Model Concept(s):
Schizophrenia;
Dendritic Action Potentials;
Action Potential Initiation;
Synaptic Integration;
Implementer(s):
Maki-Marttunen, Tuomo [tuomomm at uio.no];
Search NeuronDB
for information about:
AMPA
;
NMDA
;
Gaba
;
I Na,p
;
I Na,t
;
I L high threshold
;
I T low threshold
;
I A
;
I M
;
I h
;
I K,Ca
;
I Calcium
;
I A, slow
;
Gaba
;
Glutamate
;
/
l5pc_scz
hay
models
morphologies
README.html
Ca_HVA.mod
*
Other models using Ca_HVA.mod:
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
Schiz.-linked gene effects on intrinsic single-neuron excitability (Maki-Marttunen et al. 2016)
Ca_LVAst.mod
*
Other models using Ca_LVAst.mod:
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
Schiz.-linked gene effects on intrinsic single-neuron excitability (Maki-Marttunen et al. 2016)
CaDynamics_E2.mod
*
Other models using CaDynamics_E2.mod:
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
Schiz.-linked gene effects on intrinsic single-neuron excitability (Maki-Marttunen et al. 2016)
epsp.mod
*
Other models using epsp.mod:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Glutamate mediated dendritic and somatic plateau potentials in cortical L5 pyr cells (Gao et al '20)
Impedance spectrum in cortical tissue: implications for LFP signal propagation (Miceli et al. 2017)
L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer 5 Pyramidal Neuron (Shai et al., 2015)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
Schiz.-linked gene effects on intrinsic single-neuron excitability (Maki-Marttunen et al. 2016)
Sensory-evoked responses of L5 pyramidal tract neurons (Egger et al 2020)
Ih.mod
*
Other models using Ih.mod:
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
Schiz.-linked gene effects on intrinsic single-neuron excitability (Maki-Marttunen et al. 2016)
Im.mod
*
Other models using Im.mod:
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
Schiz.-linked gene effects on intrinsic single-neuron excitability (Maki-Marttunen et al. 2016)
K_Pst.mod
*
Other models using K_Pst.mod:
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
Schiz.-linked gene effects on intrinsic single-neuron excitability (Maki-Marttunen et al. 2016)
K_Tst.mod
*
Other models using K_Tst.mod:
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
Schiz.-linked gene effects on intrinsic single-neuron excitability (Maki-Marttunen et al. 2016)
Nap_Et2.mod
*
Other models using Nap_Et2.mod:
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
NaTa_t.mod
*
Other models using NaTa_t.mod:
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
ProbAMPANMDA2.mod
*
Other models using ProbAMPANMDA2.mod:
Layer V pyramidal cell functions and schizophrenia genetics (Mäki-Marttunen et al 2019)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
ProbUDFsyn2.mod
*
Other models using ProbUDFsyn2.mod:
Layer V pyramidal cell functions and schizophrenia genetics (Mäki-Marttunen et al 2019)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Microcircuits of L5 thick tufted pyramidal cells (Hay & Segev 2015)
SK_E2.mod
*
Other models using SK_E2.mod:
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
Schiz.-linked gene effects on intrinsic single-neuron excitability (Maki-Marttunen et al. 2016)
SKv3_1.mod
*
Other models using SKv3_1.mod:
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018)
Pleiotropic effects of SCZ-associated genes (Mäki-Marttunen et al. 2017)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
SCZ-associated variant effects on L5 pyr cell NN activity and delta osc. (Maki-Marttunen et al 2018)
Schiz.-linked gene effects on intrinsic single-neuron excitability (Maki-Marttunen et al. 2016)
calcapicalthresholds_control.py
calcapicalthresholds_epsp_control.py
calcifcurves.py
calcifcurves_comb.py
calcnspikesperburst2.py
calcsteadystate.py
calcupdown2responses.py
calcupdownresponses_noisydown.py
calcupdownresponses_noisyup.py
coding.py
coding_comb.py
coding_nonprop_comb_somaticI.py
coding_nonprop_somaticI.py
collectupdownresponses_noisy.py
control_cs.sav
controlamps_cs0.sav
controlamps_cs1.sav
controlamps_cs2.sav
controlamps_cs3.sav
controlamps_cs4.sav
controlamps_cs5.sav
controlamps_cs6.sav
drawfigcomb.py
drawnspikesperburst2.py
drawupdownresponses_noisy.py
findppicoeffs.py
findppicoeffs_comb.py
findppicoeffs_complement.py
findthresholdbasalamps_coding.py
findthresholddistalamps.py
findthresholddistalamps_coding.py
findthresholddistalamps_comb.py
mutation_stuff.py
mytools.py
*
Other models using mytools.py:
Biochemically detailed model of LTP and LTD in a cortical spine (Maki-Marttunen et al 2020)
protocol.py
runcontrols_cs.py
savebasalsynapselocations_coding.py
savesynapselocations.py
savesynapselocations_coding.py
scalemutations_cs.py
scalings_cs.sav
setparams.py
synlocs300.0.sav
File not selected
<- Select file from this column.
