MicrocircuitDB: Layer V pyramidal cell functions and schizophrenia genetics (Mäki-Marttunen et al 2019)

Layer V pyramidal cell functions and schizophrenia genetics (Mäki-Marttunen et al 2019)

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Accession:249463

Study on how GWAS-identified risk genes of shizophrenia affect excitability and integration of inputs in thick-tufted layer V pyramidal cells
Reference:
1 . Mäki-Marttunen T, Devor A, Phillips WA, Dale AM, Andreassen OA, Einevoll GT (2019) Computational modeling of genetic contributions to excitability and neural coding in layer V pyramidal cells: applications to schizophrenia pathology Front. Comput. Neurosci. 13:66

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Model Information (Click on a link to find other models with that property)

Model Type:	Neuron or other electrically excitable cell;
Brain Region(s)/Organism:	Neocortex;
Cell Type(s):
Channel(s):	I A; I M; I h; I K,Ca; I Calcium; I A, slow; I Na,t; I Na,p; I L high threshold; I T low threshold;
Gap Junctions:
Receptor(s):	AMPA; NMDA; Gaba;
Gene(s):
Transmitter(s):	Glutamate; Gaba;
Simulation Environment:	NEURON; Python;
Model Concept(s):	Schizophrenia; Dendritic Action Potentials; Action Potential Initiation; Synaptic Integration;
Implementer(s):	Maki-Marttunen, Tuomo [tuomomm at uio.no];

Search NeuronDB for information about: AMPA; NMDA; Gaba; I Na,p; I Na,t; I L high threshold; I T low threshold; I A; I M; I h; I K,Ca; I Calcium; I A, slow; Gaba; Glutamate;

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CaDynamics_E2.mod *

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ProbUDFsyn2.mod *

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calcapicalthresholds_epsp_control.py

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coding_nonprop_somaticI.py

collectupdownresponses_noisy.py

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findppicoeffs.py

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