Factors contribution to GDP-induced [Cl-]i transients (Lombardi et al 2019)

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Accession:253369
This models are used to evaluate which factors influence the GDP (giant depolarizing potential) induced [Cl-]I transients based on a initial model of P. Jedlicka
Reference:
1 . Lombardi A, Jedlicka P, Luhmann HJ, Kilb W (2019) Interactions Between Membrane Resistance, GABA-A Receptor Properties, Bicarbonate Dynamics and Cl-Transport Shape Activity-Dependent Changes of Intracellular Cl- Concentration Int J of Mol Sci [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Dendrite; Synapse;
Brain Region(s)/Organism: Mouse; Hippocampus;
Cell Type(s): Hippocampus CA3 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s): GabaA;
Gene(s):
Transmitter(s): Gaba;
Simulation Environment: NEURON;
Model Concept(s): Synaptic Plasticity;
Implementer(s):
Search NeuronDB for information about:  Hippocampus CA3 pyramidal GLU cell; GabaA; Gaba;
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LombardiEtAl2019
Real_Cell_Cl_HCO3_1GDP_Var-Cl-gPas__Fig2
cldif_CA3_NKCC1_HCO3.mod *
gabaA_Cl_HCO3.mod *
VDpas.mod *
vecevent.mod *
Cell1_Cl_HCO3_GPas.hoc
GDP_Cl_HCO3_All_short.ses *
Single_GDP_101GABA_HCO3_Div_gPas_Div_Cl.hoc
Single_GDP_101GABA_P_0_Div_gPas_30_Cl.hoc
Single_GDP_101GABA_PGABA-0_Div_gPas_Div_Cl.hoc
Single_GDP_GABA_HCO3_VDpas_Div_pGABA_Div_Cl.hoc *
start_Single_GDP_101GABA_Div_Gpas_Div_Cl.hoc
start_Single_GDP_101GABA_p_0_Div_Gpas_Cl_30.hoc
start_Single_GDP_101GABA_PGABA-0_Div_gPas_Div_Cl.hoc
start_Single_GDP_101GABA_VDpas_Div_pGABA_Div_Cl.hoc
start_Test_Rinput_IClamp.hoc
Test_Rinput_IClamp.ses
                            
// Start

load_file("nrngui.hoc")
load_file("Cell1_Cl_HCO3_GPas.hoc")
load_file("Single_GDP_101GABA_PGABA-0_Div_gPas_Div_Cl.hoc")