Striatal FSI and SPN oscillation model (Chartove et al. 2020)

 Download zip file 
Help downloading and running models
Our model consists of three interconnected populations of single or double compartment Hodgkin-Huxley neurons: a feedforward network of FSIs, and two networks of SPNs (the D1 receptor-expressing "direct pathway" subnetwork and the D2 receptor-expressing "indirect pathway" subnetwork).
1 . Chartove JA, McCarthy MM, Pittman-Polletta BR, Kopell NJ (2020) A biophysical model of striatal microcircuits suggests gamma and beta oscillations interleaved at delta/theta frequencies mediate periodicity in motor control PLOS Computational Biology 16:1-30
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Striatum;
Cell Type(s): Neostriatum medium spiny direct pathway GABA cell; Neostriatum medium spiny indirect pathway GABA cell; Neostriatum fast spiking interneuron;
Channel(s): I Potassium; I M;
Gap Junctions: Gap junctions;
Receptor(s): Dopaminergic Receptor;
Transmitter(s): Dopamine; Gaba;
Simulation Environment: DynaSim;
Model Concept(s): Oscillations; Beta oscillations; Gamma oscillations; Theta oscillations;
Implementer(s): Chartove, Julia A K [chartove at bu dot edu];
Search NeuronDB for information about:  Neostriatum medium spiny direct pathway GABA cell; Neostriatum medium spiny indirect pathway GABA cell; Dopaminergic Receptor; I M; I Potassium; Dopamine; Gaba;
%PDF2EPS  Convert a pdf file to eps format using pdftops
% Examples:
%   pdf2eps source dest
% This function converts a pdf file to eps format.
% This function requires that you have pdftops, from the Xpdf suite of
% functions, installed on your system. This can be downloaded from:
%   source - filename of the source pdf file to convert. The filename is
%            assumed to already have the extension ".pdf".
%   dest - filename of the destination eps file. The filename is assumed to
%          already have the extension ".eps".

% Copyright (C) Oliver Woodford 2009-2010

% Thanks to Aldebaro Klautau for reporting a bug when saving to
% non-existant directories.

function pdf2eps(source, dest)
% Construct the options string for pdftops
options = ['-q -paper match -eps -level2 "' source '" "' dest '"'];
% Convert to eps using pdftops
[status, message] = pdftops(options);
% Check for error
if status
    % Report error
    if isempty(message)
        error('Unable to generate eps. Check destination directory is writable.');
% Fix the DSC error created by pdftops
fid = fopen(dest, 'r+');
if fid == -1
    % Cannot open the file
fgetl(fid); % Get the first line
str = fgetl(fid); % Get the second line
if strcmp(str(1:min(13, end)), '% Produced by')
    fseek(fid, -numel(str)-1, 'cof');
    fwrite(fid, '%'); % Turn ' ' into '%'