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Molecular layer interneurons in cerebellum encode valence in associative learning (Ma et al 2020)
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Accession:
266578
We used two-photon microscopy to study the role of ensembles of cerebellar molecular layer interneurons (MLIs) in a go-no go task where mice obtain a sugar water reward. In order to begin understanding the circuit basis of our findings in changes in lick behavior with chemogenetics in the go-no go associative learning olfactory discrimination task we generated a simple computational model of MLI interaction with PCs.
Reference:
1 .
Ma M, Futia GL, De Souza FM, Ozbay BN, Llano I, Gibson EA, Restrepo D (2020) Molecular layer interneurons in the cerebellum encode for valence in associative learning
Nat Commun .
[
PubMed
]
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Model Information
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Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cerebellum;
Mouse;
Cell Type(s):
Cerebellum Purkinje GABA cell;
Cerebellum interneuron stellate GABA cell;
Channel(s):
Gap Junctions:
Receptor(s):
AMPA;
GabaA;
Gene(s):
Transmitter(s):
Gaba;
Glutamate;
Simulation Environment:
NEURON;
Model Concept(s):
Action Potentials;
Detailed Neuronal Models;
Implementer(s):
Simoes-de-Souza, Fabio [fabio.souza at ufabc.edu.br];
Search NeuronDB
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Cerebellum Purkinje GABA cell
;
Cerebellum interneuron stellate GABA cell
;
GabaA
;
AMPA
;
Gaba
;
Glutamate
;
/
MaEtAl2020
README.html
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