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Cerebellar Golgi cells, dendritic processing, and synaptic plasticity (Masoli et al 2020)
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The Golgi cells are the main inhibitory interneurons of the cerebellar granular layer. To study the mechanisms through which these neurons integrate complex input patterns, a new set of models were developed using the latest experimental information and a genetic algorithm approach to fit the maximum ionic channel conductances. The models faithfully reproduced a rich pattern of electrophysiological and pharmacological properties and predicted the operating mechanisms of these neurons.
Masoli S, Ottaviani A, Casali S, D'Angelo E (2020) Cerebellar Golgi cell models predict dendritic processing and mechanisms of synaptic plasticity.
PLoS Comput Biol
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Neuron or other electrically excitable cell;
Cerebellum golgi cell;
Action Potential Initiation;
Masoli, Stefano [stefano.masoli at unipv.it];
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