Pyramidal Neuron: Deep, Thalamic Relay and Reticular, Interneuron (Destexhe et al 1998, 2001)

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Accession:3817
This package shows single-compartment models of different classes of cortical neurons, such as the "regular-spiking", "fast-spiking" and "bursting" (LTS) neurons. The mechanisms included are the Na+ and K+ currents for generating action potentials (INa, IKd), the T-type calcium current (ICaT), and a slow voltage-dependent K+ current (IM). See http://cns.fmed.ulaval.ca/alain_demos.html
Reference:
1 . Destexhe A, Contreras D, Steriade M (1998) Mechanisms underlying the synchronizing action of corticothalamic feedback through inhibition of thalamic relay cells. J Neurophysiol 79:999-1016 [PubMed]
2 . Destexhe A, Contreras D, Steriade M (2001) LTS cells in cerebral cortex and their role in generating spike-and-wave oscillations. Neurocomputing 38:555-563
3 . Destexhe A, Sejnowski TJ (2001) Thalamocortical Assemblies-How Ion Channels, Single Neurons and large-Scale Networks Organize Sleep
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Thalamus geniculate nucleus/lateral principal GLU cell; Thalamus reticular nucleus GABA cell; Neocortex L5/6 pyramidal GLU cell; Neocortex spiking regular (RS) neuron; Neocortex spiking low threshold (LTS) neuron;
Channel(s): I Na,t; I T low threshold; I K; I M; I Sodium; I Calcium; I Potassium;
Gap Junctions:
Receptor(s): GabaA; GabaB; AMPA; Gaba;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Activity Patterns; Bursting; Action Potentials; Calcium dynamics;
Implementer(s): Destexhe, Alain [Destexhe at iaf.cnrs-gif.fr];
Search NeuronDB for information about:  Thalamus geniculate nucleus/lateral principal GLU cell; Thalamus reticular nucleus GABA cell; Neocortex L5/6 pyramidal GLU cell; GabaA; GabaB; AMPA; Gaba; I Na,t; I T low threshold; I K; I M; I Sodium; I Calcium; I Potassium;
 
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