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Steady-state Vm distribution of neurons subject to synaptic noise (Rudolph, Destexhe 2005)
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Accession:
64259
This package simulates synaptic background activity similar to in vivo measurements using a model of fluctuating synaptic conductances, and compares the simulations with analytic estimates. The steady-state membrane potential (Vm) distribution is calculated numerically and compared with the "extended" analytic expression provided in the reference (see this paper for details).
Reference:
1 .
Rudolph M, Destexhe A (2005) An extended analytic expression for the membrane potential distribution of conductance-based synaptic noise.
Neural Comput
17
:2301-15
[
PubMed
]
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Model Information
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Model Type:
Synapse;
Brain Region(s)/Organism:
Cell Type(s):
Neocortex L5/6 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s):
GabaA;
AMPA;
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Simplified Models;
Synaptic noise;
Implementer(s):
Destexhe, Alain [Destexhe at iaf.cnrs-gif.fr];
Search NeuronDB
for information about:
Neocortex L5/6 pyramidal GLU cell
;
GabaA
;
AMPA
;
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/
NCnote
readme.txt
Gfluct.mod
demo.hoc
mosinit.hoc
*
Other models using mosinit.hoc:
Phase response curve of a globus pallidal neuron (Fujita et al. 2011)
load_file("nrngui.hoc") load_file("demo.hoc")
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