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Hippocampus temporo-septal engram shift model (Lytton 1999)
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Accession:
7400
Temporo-septal engram shift model of hippocampal memory. The model posits that memories gradually move along the hippocampus from a temporal encoding site to ever more septal sites from which they are recalled. We propose that the sense of time is encoded by the location of the engram along the temporo-septal axis.
Reference:
1 .
Lytton WW, Lipton P (1999) Can the hippocampus tell time? The temporo-septal engram shift model.
Neuroreport
10
:2301-6
[
PubMed
]
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Model Information
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Model Type:
Realistic Network;
Brain Region(s)/Organism:
Hippocampus;
Cell Type(s):
Channel(s):
I Na,t;
I K;
Gap Junctions:
Receptor(s):
GabaA;
AMPA;
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Pattern Recognition;
Temporal Pattern Generation;
Spatio-temporal Activity Patterns;
Simplified Models;
Implementer(s):
Lytton, William [bill.lytton at downstate.edu];
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for information about:
GabaA
;
AMPA
;
I Na,t
;
I K
;
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lytton99
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