Citations for Hippocampal Mossy Fiber bouton: presynaptic KV7 channel function (Martinello et al 2019)

Legends: Link to a Model Reference cited by multiple papers


Martinello K, Giacalone E, Migliore M, Brown DA, Shah MM (2019) The subthreshold-active KV7 current regulates neurotransmission by limiting spike-induced Ca2+ influx in hippocampal mossy fiber synaptic terminals. Commun Biol 2:145 [PubMed]

References and models cited by this paper

References and models that cite this paper

Acsády L, Káli S (2007) Models, structure, function: the transformation of cortical signals in the dentate gyrus. Prog Brain Res 163:577-99 [Journal] [PubMed]
Alle H, Geiger JR (2006) Combined analog and action potential coding in hippocampal mossy fibers. Science 311:1290-3 [Journal] [PubMed]
Alle H, Kubota H, Geiger JR (2011) Sparse but highly efficient Kv3 outpace BKCa channels in action potential repolarization at hippocampal mossy fiber boutons. J Neurosci 31:8001-12 [Journal] [PubMed]
Battefeld A, Tran BT, Gavrilis J, Cooper EC, Kole MH (2014) Heteromeric Kv7.2/7.3 channels differentially regulate action potential initiation and conduction in neocortical myelinated axons. J Neurosci 34:3719-32 [Journal] [PubMed]
Begum R, Bakiri Y, Volynski KE, Kullmann DM (2016) Action potential broadening in a presynaptic channelopathy. Nat Commun 7:12102 [Journal] [PubMed]
Bischofberger J, Engel D, Frotscher M, Jonas P (2006) Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network. Pflugers Arch 453:361-72 [Journal] [PubMed]
Bischofberger J, Engel D, Li L, Geiger JR, Jonas P (2006) Patch-clamp recording from mossy fiber terminals in hippocampal slices. Nat Protoc 1:2075-81 [Journal] [PubMed]
Bischofberger J, Geiger JR, Jonas P (2002) Timing and efficacy of Ca2+ channel activation in hippocampal mossy fiber boutons. J Neurosci 22:10593-602 [PubMed]
Brown DA, Adams PR (1980) Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone. Nature 283:673-6 [PubMed]
Brown DA, Passmore GM (2009) Neural KCNQ (Kv7) channels. Br J Pharmacol 156:1185-95 [Journal] [PubMed]
Brown JT, Randall AD (2009) Activity-dependent depression of the spike after-depolarization generates long-lasting intrinsic plasticity in hippocampal CA3 pyramidal neurons. J Physiol 587:1265-81 [Journal] [PubMed]
Castillo PE, Weisskopf MG, Nicoll RA (1994) The role of Ca2+ channels in hippocampal mossy fiber synaptic transmission and long-term potentiation. Neuron 12:261-9 [PubMed]
Chamberland S, Timofeeva Y, Evstratova A, Volynski K, Tóth K (2018) Action potential counting at giant mossy fiber terminals gates information transfer in the hippocampus. Proc Natl Acad Sci U S A 115:7434-7439 [Journal] [PubMed]
Chicurel ME, Harris KM (1992) Three-dimensional analysis of the structure and composition of CA3 branched dendritic spines and their synaptic relationships with mossy fiber boutons in the rat hippocampus. J Comp Neurol 325:169-82 [Journal] [PubMed]
Cooper EC, Harrington E, Jan YN, Jan LY (2001) M channel KCNQ2 subunits are localized to key sites for control of neuronal network oscillations and synchronization in mouse brain. J Neurosci 21:9529-40 [PubMed]
Delvendahl I, Weyhersmüller A, Ritzau-Jost A, Hallermann S (2013) Hippocampal and cerebellar mossy fibre boutons - same name, different function. J Physiol 591:3179-88 [Journal] [PubMed]
Devaux JJ, Kleopa KA, Cooper EC, Scherer SS (2004) KCNQ2 is a nodal K+ channel. J Neurosci 24:1236-44 [Journal] [PubMed]
Dodson PD, Billups B, Rusznák Z, Szûcs G, Barker MC, Forsythe ID (2003) Presynaptic rat Kv1.2 channels suppress synaptic terminal hyperexcitability following action potential invasion. J Physiol 550:27-33 [Journal] [PubMed]
Elmedyb P, Calloe K, Schmitt N, Hansen RS, Grunnet M, Olesen SP (2007) Modulation of ERG channels by XE991. Basic Clin Pharmacol Toxicol 100:316-22 [Journal] [PubMed]
Engel D, Jonas P (2005) Presynaptic action potential amplification by voltage-gated Na+ channels in hippocampal mossy fiber boutons. Neuron 45:405-17 [Journal] [PubMed]
Fidzinski P, Korotkova T, Heidenreich M, Maier N, Schuetze S, Kobler O, Zuschratter W, Schmitz D, Ponomarenko A, Jentsch TJ (2015) KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations. Nat Commun 6:6254 [Journal] [PubMed]
Foust AJ, Yu Y, Popovic M, Zecevic D, McCormick DA (2011) Somatic membrane potential and Kv1 channels control spike repolarization in cortical axon collaterals and presynaptic boutons. J Neurosci 31:15490-8 [Journal] [PubMed]
  • Spike repolarization in axon collaterals (Foust et al. 2011) [Model]
Geiger J, Weber YG, Landwehrmeyer B, Sommer C, Lerche H (2006) Immunohistochemical analysis of KCNQ3 potassium channels in mouse brain. Neurosci Lett 400:101-4 [Journal] [PubMed]
Geiger JR, Jonas P (2000) Dynamic control of presynaptic Ca(2+) inflow by fast-inactivating K(+) channels in hippocampal mossy fiber boutons. Neuron 28:927-39 [PubMed]
Gonzalez JC, Epps SA, Markwardt SJ, Wadiche JI, Overstreet-Wadiche L (2018) Constitutive and Synaptic Activation of GIRK Channels Differentiates Mature and Newborn Dentate Granule Cells. J Neurosci 38:6513-6526 [Journal] [PubMed]
Greene DL, Kang S, Hoshi N (2017) XE991 and Linopirdine Are State-Dependent Inhibitors for Kv7/KCNQ Channels that Favor Activated Single Subunits. J Pharmacol Exp Ther 362:177-185 [Journal] [PubMed]
Henze DA, Urban NN, Barrionuevo G (2000) The multifarious hippocampal mossy fiber pathway: a review. Neuroscience 98:407-27 [PubMed]
Henze DA, Wittner L, Buzsáki G (2002) Single granule cells reliably discharge targets in the hippocampal CA3 network in vivo. Nat Neurosci 5:790-5 [Journal] [PubMed]
Hines ML, Carnevale NT (1997) The NEURON simulation environment. Neural Comput 9:1179-209 [PubMed]
Holderith N, Lorincz A, Katona G, Rózsa B, Kulik A, Watanabe M, Nusser Z (2012) Release probability of hippocampal glutamatergic terminals scales with the size of the active zone. Nat Neurosci 15:988-97 [Journal] [PubMed]
Hoppa MB, Gouzer G, Armbruster M, Ryan TA (2014) Control and plasticity of the presynaptic action potential waveform at small CNS nerve terminals. Neuron 84:778-89 [Journal] [PubMed]
Hu W, Bean BP (2018) Differential Control of Axonal and Somatic Resting Potential by Voltage-Dependent Conductances in Cortical Layer 5 Pyramidal Neurons. Neuron 97:1315-1326.e3 [Journal] [PubMed]
Huang H, Trussell LO (2011) KCNQ5 channels control resting properties and release probability of a synapse. Nat Neurosci 14:840-7 [Journal] [PubMed]
Huang Z, Lujan R, Martinez-Hernandez J, Lewis AS, Chetkovich DM, Shah MM (2012) TRIP8b-independent trafficking and plasticity of adult cortical presynaptic HCN1 channels. J Neurosci 32:14835-48 [Journal] [PubMed]
Ishikawa T, Nakamura Y, Saitoh N, Li WB, Iwasaki S, Takahashi T (2003) Distinct roles of Kv1 and Kv3 potassium channels at the calyx of Held presynaptic terminal. J Neurosci 23:10445-53 [PubMed]
Jackson MB, Redman SJ (2003) Calcium dynamics, buffering, and buffer saturation in the boutons of dentate granule-cell axons in the hilus. J Neurosci 23:1612-21 [PubMed]
Jaffe DB, Gutiérrez R (2007) Mossy fiber synaptic transmission: communication from the dentate gyrus to area CA3. Prog Brain Res 163:109-32 [Journal] [PubMed]
Jentsch TJ (2000) Neuronal KCNQ potassium channels: physiology and role in disease. Nat Rev Neurosci 1:21-30 [Journal] [PubMed]
Jones RT, Faas GC, Mody I (2014) Intracellular bicarbonate regulates action potential generation via KCNQ channel modulation. J Neurosci 34:4409-17 [Journal] [PubMed]
Kaeser PS, Regehr WG (2014) Molecular mechanisms for synchronous, asynchronous, and spontaneous neurotransmitter release. Annu Rev Physiol 76:333-63 [Journal] [PubMed]
Kavalali ET (2015) The mechanisms and functions of spontaneous neurotransmitter release. Nat Rev Neurosci 16:5-16 [Journal] [PubMed]
Kawaguchi SY, Sakaba T (2015) Control of inhibitory synaptic outputs by low excitability of axon terminals revealed by direct recording. Neuron 85:1273-88 [Journal] [PubMed]
Kole MH, Stuart GJ (2012) Signal processing in the axon initial segment. Neuron 73:235-47 [Journal] [PubMed]
Lai HC, Jan LY (2006) The distribution and targeting of neuronal voltage-gated ion channels. Nat Rev Neurosci 7:548-62 [Journal] [PubMed]
Leão RN, Tan HM, Fisahn A (2009) Kv7/KCNQ channels control action potential phasing of pyramidal neurons during hippocampal gamma oscillations in vitro. J Neurosci 29:13353-64 [Journal] [PubMed]
Li L, Bischofberger J, Jonas P (2007) Differential gating and recruitment of P/Q-, N-, and R-type Ca2+ channels in hippocampal mossy fiber boutons. J Neurosci 27:13420-9 [Journal] [PubMed]
Martinello K, Huang Z, Lujan R, Tran B, Watanabe M, Cooper EC, Brown DA, Shah MM (2015) Cholinergic afferent stimulation induces axonal function plasticity in adult hippocampal granule cells. Neuron 85:346-63 [Journal] [PubMed]
Mateos-Aparicio P, Murphy R, Storm JF (2014) Complementary functions of SK and Kv7/M potassium channels in excitability control and synaptic integration in rat hippocampal dentate granule cells. J Physiol 592:669-93 [Journal] [PubMed]
  • Dentate granule cell: mAHP & sAHP; SK & Kv7/M channels (Mateos-Aparicio et al., 2014) [Model]
Metz AE, Jarsky T, Martina M, Spruston N (2005) R-type calcium channels contribute to afterdepolarization and bursting in hippocampal CA1 pyramidal neurons. J Neurosci 25:5763-73 [Journal] [PubMed]
Nagy GA, Botond G, Borhegyi Z, Plummer NW, Freund TF, Hájos N (2013) DAG-sensitive and Ca(2+) permeable TRPC6 channels are expressed in dentate granule cells and interneurons in the hippocampal formation. Hippocampus 23:221-32 [Journal] [PubMed]
Nakamura Y, Takahashi T (2007) Developmental changes in potassium currents at the rat calyx of Held presynaptic terminal. J Physiol 581:1101-12 [Journal] [PubMed]
Pan Z, Kao T, Horvath Z, Lemos J, Sul JY, Cranstoun SD, Bennett V, Scherer SS, Cooper EC (2006) A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon. J Neurosci 26:2599-613 [Journal] [PubMed]
Pelkey KA, McBain CJ (2008) Target-cell-dependent plasticity within the mossy fibre-CA3 circuit reveals compartmentalized regulation of presynaptic function at divergent release sites. J Physiol 586:1495-502 [Journal] [PubMed]
Pernía-Andrade AJ, Jonas P (2014) Theta-gamma-modulated synaptic currents in hippocampal granule cells in vivo define a mechanism for network oscillations. Neuron 81:140-52 [Journal] [PubMed]
Peters HC, Hu H, Pongs O, Storm JF, Isbrandt D (2005) Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior. Nat Neurosci 8:51-60 [Journal] [PubMed]
Rebola N, Carta M, Mulle C (2017) Operation and plasticity of hippocampal CA3 circuits: implications for memory encoding. Nat Rev Neurosci 18:208-220 [Journal] [PubMed]
Rollenhagen A, Sätzler K, Rodríguez EP, Jonas P, Frotscher M, Lübke JH (2007) Structural determinants of transmission at large hippocampal mossy fiber synapses. J Neurosci 27:10434-44 [Journal] [PubMed]
Schwarz JR, Glassmeier G, Cooper EC, Kao TC, Nodera H, Tabuena D, Kaji R, Bostock H (2006) KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier. J Physiol 573:17-34 [Journal] [PubMed]
Scott R, Rusakov DA (2006) Main determinants of presynaptic Ca2+ dynamics at individual mossy fiber-CA3 pyramidal cell synapses. J Neurosci 26:7071-81 [Journal] [PubMed]
Shah MM, Migliore M, Valencia I, Cooper EC, Brown DA (2008) Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons. Proc Natl Acad Sci U S A 105:7869-74 [Journal] [PubMed]
  • CA1 pyramidal neuron: functional significance of axonal Kv7 channels (Shah et al. 2008) [Model]
Singh NA, Otto JF, Dahle EJ, Pappas C, Leslie JD, Vilaythong A, Noebels JL, White HS, Wilcox KS, Leppert MF (2008) Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization. J Physiol 586:3405-23 [Journal] [PubMed]
Southan AP, Robertson B (2000) Electrophysiological characterization of voltage-gated K(+) currents in cerebellar basket and purkinje cells: Kv1 and Kv3 channel subfamilies are present in basket cell nerve terminals. J Neurosci 20:114-22 [PubMed]
Stegen M, Kirchheim F, Hanuschkin A, Staszewski O, Veh RW, Wolfart J (2012) Adaptive intrinsic plasticity in human dentate gyrus granule cells during temporal lobe epilepsy. Cereb Cortex 22:2087-101 [Journal] [PubMed]
Tai C, Hines DJ, Choi HB, MacVicar BA (2011) Plasma membrane insertion of TRPC5 channels contributes to the cholinergic plateau potential in hippocampal CA1 pyramidal neurons. Hippocampus 21:958-67 [Journal] [PubMed]
Trimmer JS (2015) Subcellular localization of K+ channels in mammalian brain neurons: remarkable precision in the midst of extraordinary complexity. Neuron 85:238-56 [Journal] [PubMed]
Vervaeke K, Gu N, Agdestein C, Hu H, Storm JF (2006) Kv7/KCNQ/M-channels in rat glutamatergic hippocampal axons and their role in regulation of excitability and transmitter release. J Physiol 576:235-56 [Journal] [PubMed]
Vyleta NP, Borges-Merjane C, Jonas P (2016) Plasticity-dependent, full detonation at hippocampal mossy fiber-CA3 pyramidal neuron synapses. Elife [Journal] [PubMed]
Vyleta NP, Jonas P (2014) Loose coupling between Ca2+ channels and release sensors at a plastic hippocampal synapse. Science 343:665-70 [Journal] [PubMed]
Wang HS, Pan Z, Shi W, Brown BS, Wymore RS, Cohen IS, Dixon JE, McKinnon D (1998) KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel. Science 282:1890-3 [PubMed]
Weber YG, Geiger J, Kämpchen K, Landwehrmeyer B, Sommer C, Lerche H (2006) Immunohistochemical analysis of KCNQ2 potassium channels in adult and developing mouse brain. Brain Res 1077:1-6 [Journal] [PubMed]
Yan HD, Villalobos C, Andrade R (2009) TRPC Channels Mediate a Muscarinic Receptor-Induced Afterdepolarization in Cerebral Cortex. J Neurosci 29:10038-46 [Journal] [PubMed]
Yang YM, Wang W, Fedchyshyn MJ, Zhou Z, Ding J, Wang LY (2014) Enhancing the fidelity of neurotransmission by activity-dependent facilitation of presynaptic potassium currents. Nat Commun 5:4564 [Journal] [PubMed]
Young CC, Stegen M, Bernard R, Müller M, Bischofberger J, Veh RW, Haas CA, Wolfart J (2009) Upregulation of inward rectifier K+ (Kir2) channels in dentate gyrus granule cells in temporal lobe epilepsy. J Physiol 587:4213-33 [Journal] [PubMed]
Yue C, Remy S, Su H, Beck H, Yaari Y (2005) Proximal persistent Na+ channels drive spike afterdepolarizations and associated bursting in adult CA1 pyramidal cells. J Neurosci 25:9704-20 [Journal] [PubMed]
Yue C, Yaari Y (2006) Axo-somatic and apical dendritic Kv7/M channels differentially regulate the intrinsic excitability of adult rat CA1 pyramidal cells. J Neurophysiol 95:3480-95 [Journal] [PubMed]
(76 refs)